Prevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomes
Abstract Objectives: the objective this study was evaluating the prevalence of maternal colonization by Group B beta-hemolytic Streptococcus (GBS) in pregnant women who delivered preterm and its relationship with adverse maternal/perinatal outcomes. Methods: we carried out a retrospective cohort s...
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Instituto Materno Infantil de Pernambuco
2025-01-01
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| Series: | Revista Brasileira de Saúde Materno Infantil |
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| author | Marianna Camilo Rezende Thamirys Pereira Rodrigues Andressa Paes Medeiros de Freitas Karina Souza Lopes Edward Araujo Júnior Alberto Borges Peixoto |
| author_facet | Marianna Camilo Rezende Thamirys Pereira Rodrigues Andressa Paes Medeiros de Freitas Karina Souza Lopes Edward Araujo Júnior Alberto Borges Peixoto |
| author_sort | Marianna Camilo Rezende |
| collection | DOAJ |
| description | Abstract Objectives: the objective this study was evaluating the prevalence of maternal colonization by Group B beta-hemolytic Streptococcus (GBS) in pregnant women who delivered preterm and its relationship with adverse maternal/perinatal outcomes. Methods: we carried out a retrospective cohort study with singleton pregnancies with or without a culture for GBS (vaginal-rectum) who delivered spontaneously <37 weeks of gestation. Results: the study included 190 pregnant women, 53.1% (101/190) did not undergo culture for GBS and 46.8% (89/101) have done. Among the patients who had a culture, 13.5% (12/89) had positive culture for GBS and 86.5% (77/89) had a negative culture. Pregnant women without GBS culture had higher prevalence of preterm birth (74.3 vs. 59.6%, p=0.031) and lower prevalence of antibiotic prophylaxis (27.7 vs. 56.2%, p<0.001) than pregnant women with GBS culture. Higher prevalence of crystalline penicillin G use was observed in pregnant women with positive culture compared to pregnant women with negative culture for GBS (100 vs. 39%, p<0.0001). There was no significant association between pregnant women with or without a culture for GBS or positive and negative GBS cultures and adverse maternal/perinatal outcomes. Conclusion: No significant association was found between GBS culture or not, GBS positive or negative culture, adequate or inadequate GBS prophylaxis, and the prevalence of adverse maternal/perinatal outcomes. |
| format | Article |
| id | doaj-art-6a2f52bfcec54a3fbcbc67120d826c42 |
| institution | Kabale University |
| issn | 1806-9304 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Instituto Materno Infantil de Pernambuco |
| record_format | Article |
| series | Revista Brasileira de Saúde Materno Infantil |
| spelling | doaj-art-6a2f52bfcec54a3fbcbc67120d826c422025-01-21T07:40:40ZengInstituto Materno Infantil de PernambucoRevista Brasileira de Saúde Materno Infantil1806-93042025-01-012510.1590/1806-9304202500000182-enPrevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomesMarianna Camilo Rezendehttps://orcid.org/0009-0007-4525-525XThamirys Pereira Rodrigueshttps://orcid.org/0000-0003-4599-1007Andressa Paes Medeiros de Freitashttps://orcid.org/0000-0002-7817-2262Karina Souza Lopeshttps://orcid.org/0000-0002-0321-4683Edward Araujo Júniorhttps://orcid.org/0000-0002-6145-2532Alberto Borges Peixotohttps://orcid.org/0000-0002-1655-3609Abstract Objectives: the objective this study was evaluating the prevalence of maternal colonization by Group B beta-hemolytic Streptococcus (GBS) in pregnant women who delivered preterm and its relationship with adverse maternal/perinatal outcomes. Methods: we carried out a retrospective cohort study with singleton pregnancies with or without a culture for GBS (vaginal-rectum) who delivered spontaneously <37 weeks of gestation. Results: the study included 190 pregnant women, 53.1% (101/190) did not undergo culture for GBS and 46.8% (89/101) have done. Among the patients who had a culture, 13.5% (12/89) had positive culture for GBS and 86.5% (77/89) had a negative culture. Pregnant women without GBS culture had higher prevalence of preterm birth (74.3 vs. 59.6%, p=0.031) and lower prevalence of antibiotic prophylaxis (27.7 vs. 56.2%, p<0.001) than pregnant women with GBS culture. Higher prevalence of crystalline penicillin G use was observed in pregnant women with positive culture compared to pregnant women with negative culture for GBS (100 vs. 39%, p<0.0001). There was no significant association between pregnant women with or without a culture for GBS or positive and negative GBS cultures and adverse maternal/perinatal outcomes. Conclusion: No significant association was found between GBS culture or not, GBS positive or negative culture, adequate or inadequate GBS prophylaxis, and the prevalence of adverse maternal/perinatal outcomes.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292025000100402&lng=en&tlng=enGroup B beta-hemolytic StreptococcusScreeningPreterm deliveryAntibiotic prophylaxisAdverse maternal/perinatal outcomes |
| spellingShingle | Marianna Camilo Rezende Thamirys Pereira Rodrigues Andressa Paes Medeiros de Freitas Karina Souza Lopes Edward Araujo Júnior Alberto Borges Peixoto Prevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomes Revista Brasileira de Saúde Materno Infantil Group B beta-hemolytic Streptococcus Screening Preterm delivery Antibiotic prophylaxis Adverse maternal/perinatal outcomes |
| title | Prevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomes |
| title_full | Prevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomes |
| title_fullStr | Prevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomes |
| title_full_unstemmed | Prevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomes |
| title_short | Prevalence of Streptococcus B in pregnant women with preterm birth and its association with adverse outcomes |
| title_sort | prevalence of streptococcus b in pregnant women with preterm birth and its association with adverse outcomes |
| topic | Group B beta-hemolytic Streptococcus Screening Preterm delivery Antibiotic prophylaxis Adverse maternal/perinatal outcomes |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292025000100402&lng=en&tlng=en |
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