To cleave or not and how? The DNA exonucleases and endonucleases in immunity
DNA exonucleases and endonucleases are key executors of the genome during many physiological processes. They generate double-stranded DNA by cleaving damaged endogenous or exogenous DNA, triggering the activation of the innate immune pathways such as cGAS-STING-IFN, and enabling the body to produce...
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| Main Authors: | Mingjun Lu, Jinghong Wu, Qing Gao, Renjing Jin, Changming An, Teng Ma |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2025-03-01
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| Series: | Genes and Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352304224000163 |
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