Tacrolimus-Related Cerebral Microbleeds after Lung Transplantation

Posterior reversible encephalopathy syndrome is a well-known complication of treatment by tacrolimus. We report 2 cases of lung transplant recipients treated with tacrolimus who developed cerebral microbleeds on T2*-weighted sequences in the acute setting of posterior reversible encephalopathy syndr...

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Main Authors: L. Mechtouff, F. Piegay, J. Traclet, F. Philit, P. Boissonnat, M. Hermier, I. Durieu, T.-H. Cho, N. Nighoghossian, J.-F. Mornex
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2013/708961
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author L. Mechtouff
F. Piegay
J. Traclet
F. Philit
P. Boissonnat
M. Hermier
I. Durieu
T.-H. Cho
N. Nighoghossian
J.-F. Mornex
author_facet L. Mechtouff
F. Piegay
J. Traclet
F. Philit
P. Boissonnat
M. Hermier
I. Durieu
T.-H. Cho
N. Nighoghossian
J.-F. Mornex
author_sort L. Mechtouff
collection DOAJ
description Posterior reversible encephalopathy syndrome is a well-known complication of treatment by tacrolimus. We report 2 cases of lung transplant recipients treated with tacrolimus who developed cerebral microbleeds on T2*-weighted sequences in the acute setting of posterior reversible encephalopathy syndrome. Cerebral microbleeds may be a marker of tacrolimus-induced vasculopathy that may be detected earlier by neuropsychological and magnetic resonance imaging monitoring in transplant recipients treated with tacrolimus.
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publishDate 2013-01-01
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series Case Reports in Transplantation
spelling doaj-art-6a1cb54d16d6484c88b6899646a928c22025-08-20T02:06:06ZengWileyCase Reports in Transplantation2090-69432090-69512013-01-01201310.1155/2013/708961708961Tacrolimus-Related Cerebral Microbleeds after Lung TransplantationL. Mechtouff0F. Piegay1J. Traclet2F. Philit3P. Boissonnat4M. Hermier5I. Durieu6T.-H. Cho7N. Nighoghossian8J.-F. Mornex9Hospices Civils de Lyon, Hôpital Pierre Wertheimer, 59 Boulevard Pinel, 69677 Bron, FranceUniversité de Lyon, 69003 Lyon, FranceHospices Civils de Lyon, Hôpital Louis Pradel, 69677 Bron, FranceHospices Civils de Lyon, Hôpital Louis Pradel, 69677 Bron, FranceHospices Civils de Lyon, Hôpital Louis Pradel, 69677 Bron, FranceHospices Civils de Lyon, Hôpital Pierre Wertheimer, 59 Boulevard Pinel, 69677 Bron, FranceUniversité de Lyon, 69003 Lyon, FranceHospices Civils de Lyon, Hôpital Pierre Wertheimer, 59 Boulevard Pinel, 69677 Bron, FranceHospices Civils de Lyon, Hôpital Pierre Wertheimer, 59 Boulevard Pinel, 69677 Bron, FranceUniversité de Lyon, 69003 Lyon, FrancePosterior reversible encephalopathy syndrome is a well-known complication of treatment by tacrolimus. We report 2 cases of lung transplant recipients treated with tacrolimus who developed cerebral microbleeds on T2*-weighted sequences in the acute setting of posterior reversible encephalopathy syndrome. Cerebral microbleeds may be a marker of tacrolimus-induced vasculopathy that may be detected earlier by neuropsychological and magnetic resonance imaging monitoring in transplant recipients treated with tacrolimus.http://dx.doi.org/10.1155/2013/708961
spellingShingle L. Mechtouff
F. Piegay
J. Traclet
F. Philit
P. Boissonnat
M. Hermier
I. Durieu
T.-H. Cho
N. Nighoghossian
J.-F. Mornex
Tacrolimus-Related Cerebral Microbleeds after Lung Transplantation
Case Reports in Transplantation
title Tacrolimus-Related Cerebral Microbleeds after Lung Transplantation
title_full Tacrolimus-Related Cerebral Microbleeds after Lung Transplantation
title_fullStr Tacrolimus-Related Cerebral Microbleeds after Lung Transplantation
title_full_unstemmed Tacrolimus-Related Cerebral Microbleeds after Lung Transplantation
title_short Tacrolimus-Related Cerebral Microbleeds after Lung Transplantation
title_sort tacrolimus related cerebral microbleeds after lung transplantation
url http://dx.doi.org/10.1155/2013/708961
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