Efectiveness and safety of very low calory diets in obese patients
Purpose: To evaluate effectiveness, safety and adherence of Very Low Calory Diet (VLCD) in patients with obesity. Methods: Observational prospective descriptive study. Patients with BMI >30 kg/m2 who started VLCD were included. We arranged 3 pharmacotherapeutical consultations, picking up the v...
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Elsevier
2014-01-01
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| Series: | Farmacia Hospitalaria |
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| Online Access: | http://www.aulamedica.es/fh/pdf/978.pdf |
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| author | M. Sáez Belló C. Segarra Villalba E. Gras Colomer P. Frias Ruiz M. Climente Martí |
| author_facet | M. Sáez Belló C. Segarra Villalba E. Gras Colomer P. Frias Ruiz M. Climente Martí |
| author_sort | M. Sáez Belló |
| collection | DOAJ |
| description | Purpose: To evaluate effectiveness, safety and adherence of Very Low Calory Diet (VLCD) in patients with obesity.
Methods: Observational prospective descriptive study. Patients with BMI >30 kg/m2 who started VLCD were included. We arranged 3 pharmacotherapeutical consultations, picking up the variables: age, sex, BMI, side effects and number of VLCD cycles. We defined effectiveness as weight loss in absolute and relative terms and weight loss rate (kg/week); safety as incidence and severity of side effects by the Farmacovigilance Spanish System (SEFV); and adherence by a SMAQ adapted questionnaire.
Results: 29 women and 15 men were included, with a mean of 42 years. 5 patients did not complete the follow-up. Effectiveness: weight loss average was 7kg (IQR 9,5 a 5,3) and relative of 6,7%, (p < 0.0005). The weight loss rate was 1,2kg per week (IQR 1,6 a 0,9). Safety: 33% of the patients described side effects. All of them were mild (37% constipation, 16% dizziness, 12% anxiety, 5% headache, 2% gases y 2% epigastrical pain). Adherence: 84% of the patients were adherent by the SMAQ adapted questionnaire: 74% in the first cycle and 92% in the following ones. The relation between the number of cycles and the adherence did not get statistical differences (p = 0,1127).
Conclusions: Effectiveness and adherence to the treatment could improve in obese patients by setting interdisciplinary measures in the daily clinical practice. |
| format | Article |
| id | doaj-art-6a181fd5b28f4e4f8243ff5525ee12aa |
| institution | DOAJ |
| issn | 1130-6343 2171-8695 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Farmacia Hospitalaria |
| spelling | doaj-art-6a181fd5b28f4e4f8243ff5525ee12aa2025-08-20T02:56:46ZengElsevierFarmacia Hospitalaria1130-63432171-86952014-01-01381505610.7399/FH.2014.38.1.978Efectiveness and safety of very low calory diets in obese patientsM. Sáez Belló0C. Segarra Villalba1E. Gras Colomer2P. Frias Ruiz3M. Climente Martí4Servicio de Farmacia. Hospital Univesitario Dr. Peset. Valencia.Servicio de Farmacia. Hospital Univesitario Dr. Peset. ValenciaServicio de Farmacia. Hospital Univesitario Dr. Peset. Valencia. Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana (FISABIO). Valencia. España.Servicio de Farmacia. Hospital Univesitario Dr. Peset. ValenciaServicio de Farmacia. Hospital Univesitario Dr. Peset. ValenciaPurpose: To evaluate effectiveness, safety and adherence of Very Low Calory Diet (VLCD) in patients with obesity. Methods: Observational prospective descriptive study. Patients with BMI >30 kg/m2 who started VLCD were included. We arranged 3 pharmacotherapeutical consultations, picking up the variables: age, sex, BMI, side effects and number of VLCD cycles. We defined effectiveness as weight loss in absolute and relative terms and weight loss rate (kg/week); safety as incidence and severity of side effects by the Farmacovigilance Spanish System (SEFV); and adherence by a SMAQ adapted questionnaire. Results: 29 women and 15 men were included, with a mean of 42 years. 5 patients did not complete the follow-up. Effectiveness: weight loss average was 7kg (IQR 9,5 a 5,3) and relative of 6,7%, (p < 0.0005). The weight loss rate was 1,2kg per week (IQR 1,6 a 0,9). Safety: 33% of the patients described side effects. All of them were mild (37% constipation, 16% dizziness, 12% anxiety, 5% headache, 2% gases y 2% epigastrical pain). Adherence: 84% of the patients were adherent by the SMAQ adapted questionnaire: 74% in the first cycle and 92% in the following ones. The relation between the number of cycles and the adherence did not get statistical differences (p = 0,1127). Conclusions: Effectiveness and adherence to the treatment could improve in obese patients by setting interdisciplinary measures in the daily clinical practice.http://www.aulamedica.es/fh/pdf/978.pdfObesity;Pharmaceutical attentionVery Low Calory Diet (VLCD). |
| spellingShingle | M. Sáez Belló C. Segarra Villalba E. Gras Colomer P. Frias Ruiz M. Climente Martí Efectiveness and safety of very low calory diets in obese patients Farmacia Hospitalaria Obesity; Pharmaceutical attention Very Low Calory Diet (VLCD). |
| title | Efectiveness and safety of very low calory diets in obese patients |
| title_full | Efectiveness and safety of very low calory diets in obese patients |
| title_fullStr | Efectiveness and safety of very low calory diets in obese patients |
| title_full_unstemmed | Efectiveness and safety of very low calory diets in obese patients |
| title_short | Efectiveness and safety of very low calory diets in obese patients |
| title_sort | efectiveness and safety of very low calory diets in obese patients |
| topic | Obesity; Pharmaceutical attention Very Low Calory Diet (VLCD). |
| url | http://www.aulamedica.es/fh/pdf/978.pdf |
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