Utilisation of an in vivo malaria model to provide functional proof for RhopH1/CLAG essentiality and conserved orthology with P. falciparum

Abstract Background Malaria parasites establish new permeation pathways (NPPs) at the red blood cell membrane to facilitate the transport of essential nutrients from the blood plasma into the infected host cell. The NPPs are critical to parasite survival and, therefore, in the pursuit of novel thera...

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Bibliographic Details
Main Authors: Mitchell L. Trickey, Mrittika Chowdury, Georgina Bramwell, Natalie A. Counihan, Tania F. de Koning-Ward
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Biomedical Science
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Online Access:https://doi.org/10.1186/s12929-024-01105-7
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