Synthesis, and antibacterial activities of novel 1,3,4a,9-tetraza-4H-fluoren-2-amines incorporating phenoxy-N-arylacetamide, pyrazole, and 2-(4-(1-phenyl-1H-pyrazol-3-yl)phenoxy)-N-arylacetamide moieties

Synthesis, and antibacterial activities of novel 1,3,4a,9-tetraza-4H-fluoren-2-amines incorporating phenoxy-N-arylacetamide, pyrazole, and 2-(4-(1-phenyl-1H-pyrazol-3-yl)phenoxy)-N-arylacetamide moieties

Abstract A ring annelation reaction was used to successfully prepare benzo[4,5]imidazo[1,2-a][1,3,5]triazines (Systematic Name: 1,3,4a,9-tetraza-4H-fluoren-2-amines) tethered to phenoxy-N-arylacetamide, pyrazole, and 2-(4-(1-phenyl-1H-pyrazol-3-yl)phenoxy)-N-arylacetamide moieties utilizing 1-(1H-be...

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Bibliographic Details
Main Authors: Reham E. Abdelwahab, Ahmed H. M. Elwahy, Nada S. Ibrahim, Amr M. Abdelmoniem, Ismail A. Abdelhamid
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Chemistry
Subjects:
Ring annelation
1-(1H-benzo[d]imidazol-2-yl)guanidine
1,3,4a,9-tetraza-4H-fluoren-2-amines
phenoxy-N-arylacetamide
Trans esterification
Antibacterial activity
Online Access:https://doi.org/10.1186/s13065-025-01421-5
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