Intraoperatively preventive intraperitoneal perfusion chemotherapy with lobaplatin in colorectal cancer: a prospective, randomised, controlled, multicentre study

Intraoperatively preventive intraperitoneal perfusion chemotherapy with lobaplatin in colorectal cancer: a prospective, randomised, controlled, multicentre study

Abstract Background Peritoneal metastasis (PM) after radical surgery is an important cause of treatment failure in colorectal cancer (CRC). Intraoperative intraperitoneal perfusion chemotherapy may be an effective method for preventing postoperative PM in patients with CRC. This study aimed to explo...

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Main Authors: Hao Su, Rui Zhang, Yunfeng Li, Yanke Li, Wei Pei, Zhigang Jie, Zhimin Liu, Meijin Huang, Jing Zhuang, Qian Jiang, Ming Xie, Guiying Wang, Wenbin Zhang, Ming Liu, Jiansi Chen, Zejun Wang, Kang Wang, Xinghong Zhang, Guoxin Li, Xiangfu Zeng, Xinxiang Li, Xuejun Sun, Ju Wang, Dongzhu Zeng, Changlong Zhuang, Haitao Zhou, Xishan Wang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medicine
Subjects:
Peritoneal metastases
Colorectal cancer
Intraperitoneal perfusion chemotherapy
Recurrence-free survival
Online Access:https://doi.org/10.1186/s12916-025-04180-1
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