Agent-based modeling for personalized prediction of an experimental immune response to immunotherapeutic antibodies.
Targeting immune checkpoint pathways to evoke an immune response against tumors has revolutionized clinical oncology over the last decade. Antibodies that block the PD-1/PD-L1 pathway have demonstrated effective antitumor activity in cancer patients and are approved for treatment of several differen...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0324618 |
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