Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysis

Abstract Background Cancer is a disease that occurs when abnormal cells grow uncontrollably, invade other cells, and spread to different parts of the body, leading to illness and, if left untreated, death. Patients with cancer are vulnerable to malnutrition as a result of the combined effects of the...

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Main Authors: Abdi Birhanu, Monas Kitessa, Usmael Jibro, Dawit Firdisa, Obsan Kassa, Jerman Dereje, Alemayehu Deresa, Nesredin Ahmed, Lamesa Abdissa, Shambel Nigussie, Magarsa Lami
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Language:English
Published: BMC 2025-04-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-025-22606-6
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author Abdi Birhanu
Monas Kitessa
Usmael Jibro
Dawit Firdisa
Obsan Kassa
Jerman Dereje
Alemayehu Deresa
Nesredin Ahmed
Lamesa Abdissa
Shambel Nigussie
Magarsa Lami
author_facet Abdi Birhanu
Monas Kitessa
Usmael Jibro
Dawit Firdisa
Obsan Kassa
Jerman Dereje
Alemayehu Deresa
Nesredin Ahmed
Lamesa Abdissa
Shambel Nigussie
Magarsa Lami
author_sort Abdi Birhanu
collection DOAJ
description Abstract Background Cancer is a disease that occurs when abnormal cells grow uncontrollably, invade other cells, and spread to different parts of the body, leading to illness and, if left untreated, death. Patients with cancer are vulnerable to malnutrition as a result of the combined effects of the disease and its treatment. Malnutrition is a common problem among cancer patients. To design strategies and policies on health education, screening, and early intervention, a systematic review and meta-analysis are needed to highlight the burden of malnutrition among cancer patients in Ethiopia. Methods Electronic databases (SCOPUS, CINAHL, CAB Abstract, EMBASE, PubMed, and Web of Science), Google Scholar, and lists of references were used to search works of literature in Ethiopia. STATA version 17 was used for analysis, and the odds ratios of the outcome variable were determined using the random-effects model. Computing values assessed heterogeneity among the studies for I2 and P-values. Also, graphical diagnostic of small-study effect analysis was done using funnel plot to assess the publication bias. Results A total of ten studies were included with a total of 2,020 participants. This study revealed a pooled prevalence of malnutrition among cancer patients was 49.2% (95% CI: 35.5%, 63%). The subgroup analysis based on publication year revealed varying prevalence rates of malnutrition among cancer patients in Ethiopia. In 2020, a high prevalence of 86.5% (95% CI: 0.825, 0.904) was observed in Addis Ababa, the capital city. For the studies conducted in 2021, the prevalence ranged from 17.1 to 58.2% (95% CI: 0.053, 0.725). In 2022, the prevalence ranged from 48.1 to 56.7% (95% CI: 0.422, 0.54). Finally, in 2023, the prevalence ranged from 19.3 to 61.4% (95% CI: 0.048, 0.692). Conclusion This meta-analysis revealed a high prevalence of malnutrition among cancer patients in Ethiopia. The findings underscore the need for systematic screening and effective nutritional interventions for individuals with cancer in Ethiopia. The study highlights the importance of a multidisciplinary approach involving healthcare professionals to optimize patient care and outcomes.
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spelling doaj-art-69feb88a488a4ae4b940c2a0d8265c632025-08-20T03:09:21ZengBMCBMC Public Health1471-24582025-04-012511810.1186/s12889-025-22606-6Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysisAbdi Birhanu0Monas Kitessa1Usmael Jibro2Dawit Firdisa3Obsan Kassa4Jerman Dereje5Alemayehu Deresa6Nesredin Ahmed7Lamesa Abdissa8Shambel Nigussie9Magarsa Lami10School of Medicine, College of Health and Medical Sciences, Haramaya UniversityDepartment of Pharmacology, School of Pharmacy, College of Health and Medical Sciences, Haramaya UniversitySchool of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya UniversitySchool of Public Health, College of Health and Medical Sciences, Haramaya UniversitySchool of Public Health, College of Health and Medical Sciences, Haramaya UniversityDepartment of Psychiatry, School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya UniversitySchool of Public Health, College of Health and Medical Sciences, Haramaya UniversitySchool of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya UniversitySchool of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya UniversityDepartment of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya UniversitySchool of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya UniversityAbstract Background Cancer is a disease that occurs when abnormal cells grow uncontrollably, invade other cells, and spread to different parts of the body, leading to illness and, if left untreated, death. Patients with cancer are vulnerable to malnutrition as a result of the combined effects of the disease and its treatment. Malnutrition is a common problem among cancer patients. To design strategies and policies on health education, screening, and early intervention, a systematic review and meta-analysis are needed to highlight the burden of malnutrition among cancer patients in Ethiopia. Methods Electronic databases (SCOPUS, CINAHL, CAB Abstract, EMBASE, PubMed, and Web of Science), Google Scholar, and lists of references were used to search works of literature in Ethiopia. STATA version 17 was used for analysis, and the odds ratios of the outcome variable were determined using the random-effects model. Computing values assessed heterogeneity among the studies for I2 and P-values. Also, graphical diagnostic of small-study effect analysis was done using funnel plot to assess the publication bias. Results A total of ten studies were included with a total of 2,020 participants. This study revealed a pooled prevalence of malnutrition among cancer patients was 49.2% (95% CI: 35.5%, 63%). The subgroup analysis based on publication year revealed varying prevalence rates of malnutrition among cancer patients in Ethiopia. In 2020, a high prevalence of 86.5% (95% CI: 0.825, 0.904) was observed in Addis Ababa, the capital city. For the studies conducted in 2021, the prevalence ranged from 17.1 to 58.2% (95% CI: 0.053, 0.725). In 2022, the prevalence ranged from 48.1 to 56.7% (95% CI: 0.422, 0.54). Finally, in 2023, the prevalence ranged from 19.3 to 61.4% (95% CI: 0.048, 0.692). Conclusion This meta-analysis revealed a high prevalence of malnutrition among cancer patients in Ethiopia. The findings underscore the need for systematic screening and effective nutritional interventions for individuals with cancer in Ethiopia. The study highlights the importance of a multidisciplinary approach involving healthcare professionals to optimize patient care and outcomes.https://doi.org/10.1186/s12889-025-22606-6MalnutritionPooled prevalenceCancer patientsSystematic reviewMeta-analysisEthiopia
spellingShingle Abdi Birhanu
Monas Kitessa
Usmael Jibro
Dawit Firdisa
Obsan Kassa
Jerman Dereje
Alemayehu Deresa
Nesredin Ahmed
Lamesa Abdissa
Shambel Nigussie
Magarsa Lami
Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysis
BMC Public Health
Malnutrition
Pooled prevalence
Cancer patients
Systematic review
Meta-analysis
Ethiopia
title Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysis
title_full Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysis
title_fullStr Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysis
title_full_unstemmed Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysis
title_short Burden of malnutrition among cancer patients in Ethiopia: a systematic review and meta-analysis
title_sort burden of malnutrition among cancer patients in ethiopia a systematic review and meta analysis
topic Malnutrition
Pooled prevalence
Cancer patients
Systematic review
Meta-analysis
Ethiopia
url https://doi.org/10.1186/s12889-025-22606-6
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