The peculiarities of eosinophil apoptosis damage in patients with severe therapy-resistant bronchial asthma

The peculiarities of eosinophil apoptosis damage in patients with severe therapy-resistant bronchial asthma

The study aim: to investigate the dynamics of transcription factor p53, proapoptoic (bax, bcl-XS), antiapoptotic (bcl-2, bcl-XL) effectors, IL-5 expression in peripheral blood eosinophils of patients with severe therapy-resistant bronchial asthma (BA). Methods: clinical, functional, allergologic obs...

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Bibliographic Details
Main Authors: L. Yu. Nikitina, F. I. Petrovsky, I. I. Ivanchuk, A. E. Sazonov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2005-12-01
Series:Бюллетень сибирской медицины
Subjects:
therapy-resistant severe asthma
eosinophil
apoptosis
p53
bcl-2
bax
Online Access:https://bulletin.ssmu.ru/jour/article/view/3697
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