The food dye Tartrazine disrupts vascular formation both in zebrafish larvae and in human primary endothelial cells

The food dye Tartrazine disrupts vascular formation both in zebrafish larvae and in human primary endothelial cells

Abstract Tartrazine (E102) is a controversial coloring agent whose potential impacts on human health are not fully understood. Our study reveals the vascular disrupting effects of tartrazine (TTZ) on developing zebrafish embryos in vivo and on human umbilical vein endothelial cells in vitro. The dye...

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Bibliographic Details
Main Authors: Dinh Duy Thanh, Nguyen Bich-Ngoc, Cécile Paques, Aurélie Christian, Stéphanie Herkenne, Ingrid Struman, Marc Muller
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Tartrazine
Blood vessels, Zebrafish
HUVEC
BMP pathways
Rho GTPases
Online Access:https://doi.org/10.1038/s41598-024-82076-5
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