Periosteum-derived mesenchymal stem cell alleviates renal fibrosis through mTOR-mediated Treg differentiation

Periosteum-derived mesenchymal stem cell alleviates renal fibrosis through mTOR-mediated Treg differentiation

Background Mesenchymal stem cells (MSCs) are the hotspots of cellular therapy due to their low immunogenicity, potent immunoregulation, and unique renoprotection. The present study aimed to investigate the effects of periosteum-derived MSCs (PMSCs) in ischemia–reperfusion (IR)-mediated renal fibrosi...

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Main Authors: Yongsheng Luo, Kuanxin Zhang, Jiaheng Wu, Hao Zeng, Juntao Chen, Pingbao Zhang, Jingjing Guo, Cuidi Xu, Xinhao Niu, Yin Celeste Cheuk, Shihao Xu, Yirui Cao, Yufeng Zhao, Dong Zhu, Xuanchuan Wang, Ruiming Rong
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
Subjects:
Renal fibrosis
mesenchymal stem cell
regulatory T cells
mTOR
ischemia–reperfusion
kidney transplantation
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2023.2212079
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