Intrapleural pressure-controlled piezo-catalytic nanozyme for the inhibition of malignant pleural effusion

Intrapleural pressure-controlled piezo-catalytic nanozyme for the inhibition of malignant pleural effusion

Abstract Malignant pleural effusion (MPE), persistently generated by thorax tumor cells at the advanced stage, remains a major challenge for cancer therapy. Herein, we develop an ultra-sensitive piezoelectric nano-system by doping ytterbium in metal-organic framework (O3P@LPYU), which can be trigger...

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Bibliographic Details
Main Authors: Zihan Xu, Xiujing He, Yu Gui, Lingkai Tang, Yuxin Zhao, Linlin Song, Tianyue Xu, Meixu Chen, Yujie Zhao, Peixin Du, Xin Wang, Siyi Chen, Yong Luo, Feng Luo, Huan Meng, Jianping Hu, Wei Zhuo, Jing Jing, Hubing Shi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58354-9
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