Suppression of mechanical hypersensitivity and change in the expression of the dopamine D2 receptor by administration of anti-CGRP antibody into the trigeminal ganglion in trigeminal neuropathic pain model rats.
Calcitonin gene-related peptide (CGRP) and dopamine D2 receptor (D2 receptor) are associated with neuropathic pain. However, their relationship is not well understood. To better establish their relationship in trigeminal neuropathic pain, we examined male rats with infraorbital nerve (ION) ligation....
Saved in:
| Main Authors: | Hiroharu Maegawa, Nayuka Usami, Chiho Kudo, Hitoshi Niwa |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0323810 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine–endocannabinoid mechanism relevant to migraine
by: Isabella Mai Christiansen, et al.
Published: (2025-06-01) -
Sphenopalatine ganglion stimulation for the treatment of trigeminal neuropathic pain
by: Paweł Sokal, et al.
Published: (2025-05-01) -
RAMP1-dependent hormonal regulation of CGRP and its receptor in the trigeminal ganglion
by: Anja Holm, et al.
Published: (2025-06-01) -
Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not sorted into axons
by: Sofia Lyng Wæver, et al.
Published: (2025-01-01) -
Trigeminal semilunar ganglion stimulation modulates default mode network connectivity in trigeminal neuralgia
by: Bowen Chang, et al.
Published: (2025-07-01)