Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue

Dengue Hemorrhagic Fever diagnosis is supported by examining Blue Plasma Lymphocytes and C-Reactive Protein, in which Blue Plasma Lymphocytes can distinguish Dengue and Non-Dengue infections. At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections suc...

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Main Authors: Ayu Safitri Sholihah, I Gusti Ayu Nyoman Danuyanti, Siti Zaetun, Pancawati Ariami, Ersandhi Resnhaleksmana
Format: Article
Language:English
Published: Faculty of Medicine at Universitas Andalas 2022-12-01
Series:Jurnal Kesehatan Andalas
Online Access:http://jurnal.fk.unand.ac.id/index.php/jka/article/view/2032
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author Ayu Safitri Sholihah
I Gusti Ayu Nyoman Danuyanti
Siti Zaetun
Pancawati Ariami
Ersandhi Resnhaleksmana
author_facet Ayu Safitri Sholihah
I Gusti Ayu Nyoman Danuyanti
Siti Zaetun
Pancawati Ariami
Ersandhi Resnhaleksmana
author_sort Ayu Safitri Sholihah
collection DOAJ
description Dengue Hemorrhagic Fever diagnosis is supported by examining Blue Plasma Lymphocytes and C-Reactive Protein, in which Blue Plasma Lymphocytes can distinguish Dengue and Non-Dengue infections. At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. Objectives: To analyzed the correlation of the number of Blue Plasma Lymphocytes with C-Reactive Protein (CRP) levels in Dengue Hemorrhagic Fever patients. Methods: This study was analytical observational research with a cross-sectional design. The sample used was a patient diagnosed with DHF with a positive Nonstructural protein 1 (NS1) or Rapid Diagnostic Test (RDT) IgG/IgM result. The data was collected and analyzed using Spearman's rank statistical test. Results: The average number of Blue Plasma Lymphocytes in positive samples was 8%, with the number of negative results, namely 4 (13.33%) samples and 26 (86.67%) samples with positive Blue Plasma Lymphocyte results. The average level of C–Reactive Protein in the positive samples was 29.36 mg/L, with results that had normal levels were 11 (36.67%) samples and 19 (63.33%) samples with abnormal C-Reactive Protein levels. Spearman's Rank statistical test results obtained a value of p = 0.000 < 0.05, indicating a correlation between the number of Blue Plasma Lymphocytes and C–Reactive  Protein levels in Dengue Hemorrhagic Fever patients. Conclusion: The more Blue Plasma Lymphocytes, the higher C–Reactive Protein levels in Dengue Hemorrhagic Fever. Keywords: blue plasma lymphocytes, C–reactive protein, dengue hemorrhagic fever
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institution Kabale University
issn 2301-7406
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language English
publishDate 2022-12-01
publisher Faculty of Medicine at Universitas Andalas
record_format Article
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spelling doaj-art-69e27129937d45d3b6726aeceddcfb862025-02-03T03:39:53ZengFaculty of Medicine at Universitas AndalasJurnal Kesehatan Andalas2301-74062615-11382022-12-0111211111710.25077/jka.v11i2.20321222Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah DengueAyu Safitri Sholihah0I Gusti Ayu Nyoman Danuyanti1Siti Zaetun2Pancawati Ariami3Ersandhi Resnhaleksmana4Teknologi Laboratorium Medis, Poltekkes Kemenkes MataramTeknologi Laboratorium Medis, Poltekkes Kemenkes MataramTeknologi Laboratorium Medis, Poltekkes Kemenkes MataramTeknologi Laboratorium Medis, Poltekkes Kemenkes MataramTeknologi Laboratorium Medis, Poltekkes Kemenkes MataramDengue Hemorrhagic Fever diagnosis is supported by examining Blue Plasma Lymphocytes and C-Reactive Protein, in which Blue Plasma Lymphocytes can distinguish Dengue and Non-Dengue infections. At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. Objectives: To analyzed the correlation of the number of Blue Plasma Lymphocytes with C-Reactive Protein (CRP) levels in Dengue Hemorrhagic Fever patients. Methods: This study was analytical observational research with a cross-sectional design. The sample used was a patient diagnosed with DHF with a positive Nonstructural protein 1 (NS1) or Rapid Diagnostic Test (RDT) IgG/IgM result. The data was collected and analyzed using Spearman's rank statistical test. Results: The average number of Blue Plasma Lymphocytes in positive samples was 8%, with the number of negative results, namely 4 (13.33%) samples and 26 (86.67%) samples with positive Blue Plasma Lymphocyte results. The average level of C–Reactive Protein in the positive samples was 29.36 mg/L, with results that had normal levels were 11 (36.67%) samples and 19 (63.33%) samples with abnormal C-Reactive Protein levels. Spearman's Rank statistical test results obtained a value of p = 0.000 < 0.05, indicating a correlation between the number of Blue Plasma Lymphocytes and C–Reactive  Protein levels in Dengue Hemorrhagic Fever patients. Conclusion: The more Blue Plasma Lymphocytes, the higher C–Reactive Protein levels in Dengue Hemorrhagic Fever. Keywords: blue plasma lymphocytes, C–reactive protein, dengue hemorrhagic feverhttp://jurnal.fk.unand.ac.id/index.php/jka/article/view/2032
spellingShingle Ayu Safitri Sholihah
I Gusti Ayu Nyoman Danuyanti
Siti Zaetun
Pancawati Ariami
Ersandhi Resnhaleksmana
Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
Jurnal Kesehatan Andalas
title Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
title_full Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
title_fullStr Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
title_full_unstemmed Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
title_short Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
title_sort korelasi temuan limfosit plasma biru dengan kadar c reaktif protein sebagai penunjang dalam diagnosis demam berdarah dengue
url http://jurnal.fk.unand.ac.id/index.php/jka/article/view/2032
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