The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus
Kidney involvement is frequent in patients with systemic lupus erythematosus (SLE), although it may not be present from disease onset. Renal lupus itself is highly heterogenous with respect to the combination and/or severity of clinical and/or laboratory manifestations. This is a case of a 45-year-o...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2020/7869216 |
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| author | Sophia Lionaki George Liapis Kalliope Vallianou Chrysovalantis Vergadis Ioannis Boletis |
| author_facet | Sophia Lionaki George Liapis Kalliope Vallianou Chrysovalantis Vergadis Ioannis Boletis |
| author_sort | Sophia Lionaki |
| collection | DOAJ |
| description | Kidney involvement is frequent in patients with systemic lupus erythematosus (SLE), although it may not be present from disease onset. Renal lupus itself is highly heterogenous with respect to the combination and/or severity of clinical and/or laboratory manifestations. This is a case of a 45-year-old Caucasian female with an established diagnosis of SLE, who presented four times with new onset of proteinuria during a follow-up time of ten years, since the diagnosis of SLE. Specifically, she experienced two episodes of lupus membranous nephropathy, and after she achieved remission, she developed twice overt nephrotic syndrome associated with new and biopsy proven lupus podocytopathy. All these episodes of nephrotic syndrome were combined with systemic symptoms, attributed to lupus itself, while serological activity of lupus was also noted. This case highlights the importance of performing a kidney biopsy in all patients with SLE who have new renal manifestations, including nephrotic proteinuria. |
| format | Article |
| id | doaj-art-69db4ef2b03540129b60ec0177bd0961 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-69db4ef2b03540129b60ec0177bd09612025-08-20T03:34:05ZengWileyCase Reports in Nephrology2090-66412090-665X2020-01-01202010.1155/2020/78692167869216The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus ErythematosusSophia Lionaki0George Liapis1Kalliope Vallianou2Chrysovalantis Vergadis3Ioannis Boletis4Nephrology Department and Transplantation Unit, Laiko Hospital, National & Kapodistrian University of Athens, Faculty of Medicine, Athens, GreecePathology Department, Laiko Hospital, Athens, GreeceNephrology Department and Transplantation Unit, Laiko Hospital, National & Kapodistrian University of Athens, Faculty of Medicine, Athens, GreeceRadiology Department, Laiko Hospital, Athens, GreeceNephrology Department and Transplantation Unit, Laiko Hospital, National & Kapodistrian University of Athens, Faculty of Medicine, Athens, GreeceKidney involvement is frequent in patients with systemic lupus erythematosus (SLE), although it may not be present from disease onset. Renal lupus itself is highly heterogenous with respect to the combination and/or severity of clinical and/or laboratory manifestations. This is a case of a 45-year-old Caucasian female with an established diagnosis of SLE, who presented four times with new onset of proteinuria during a follow-up time of ten years, since the diagnosis of SLE. Specifically, she experienced two episodes of lupus membranous nephropathy, and after she achieved remission, she developed twice overt nephrotic syndrome associated with new and biopsy proven lupus podocytopathy. All these episodes of nephrotic syndrome were combined with systemic symptoms, attributed to lupus itself, while serological activity of lupus was also noted. This case highlights the importance of performing a kidney biopsy in all patients with SLE who have new renal manifestations, including nephrotic proteinuria.http://dx.doi.org/10.1155/2020/7869216 |
| spellingShingle | Sophia Lionaki George Liapis Kalliope Vallianou Chrysovalantis Vergadis Ioannis Boletis The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus Case Reports in Nephrology |
| title | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
| title_full | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
| title_fullStr | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
| title_full_unstemmed | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
| title_short | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
| title_sort | various forms of nephrotic syndrome in a patient with systemic lupus erythematosus |
| url | http://dx.doi.org/10.1155/2020/7869216 |
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