Heterogeneous immune landscapes and macrophage dynamics in primary and lung metastatic adenoid cystic carcinoma of the head and neck

Heterogeneous immune landscapes and macrophage dynamics in primary and lung metastatic adenoid cystic carcinoma of the head and neck

IntroductionRecurrent or metastatic adenoid cystic carcinoma (ACC) of the head and neck is rare and highly aggressive. Due to the ineffectiveness of immune checkpoint therapies, this study aims to investigate the tumor immune microenvironment of primary tumor tissues and lung metastatic tissues and...

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Bibliographic Details
Main Authors: Xuelian Wang, Tingyao Ma, Hongfei Liu, Shujing Zhang, Guoliang Yang, Yue Zhao, Lu Kong, Ran Gao, Xiaohong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
adenoid cystic carcinoma
lung metastasis
tumor immune microenvironment
tumor-associated macrophage
immune evasion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1483887/full
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