Ulcerative colitis complicated with Fournier’s gangrene: A case report

Ulcerative colitis (UC) is a chronic immune-mediated inflammatory disorder affecting the colon, which displays an increasing incidence worldwide and is characterized by symptoms of rectal inflammation such as rectal bleeding, tenesmus and multiple stools daily. The diagnosis of UC is not easy to est...

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Main Authors: Irina Bondoc, Marius Zamfir, Mara Mardare, Andrei Văcărașu, Alin Burlacu, Leila Ali, Ariana Hudita, Bianca Galateanu, Octav Ginghină, Georgios Georgiadis, Charalampos Mamoulakis
Format: Article
Language:English
Published: European Publishing 2023-01-01
Series:Public Health and Toxicology
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Online Access:https://www.publichealthtoxicology.com/Ulcerative-colitis-complicated-with-Fournier-s-gangrene-nA-case-report,159116,0,2.html
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author Irina Bondoc
Marius Zamfir
Mara Mardare
Andrei Văcărașu
Alin Burlacu
Leila Ali
Ariana Hudita
Bianca Galateanu
Octav Ginghină
Georgios Georgiadis
Charalampos Mamoulakis
author_facet Irina Bondoc
Marius Zamfir
Mara Mardare
Andrei Văcărașu
Alin Burlacu
Leila Ali
Ariana Hudita
Bianca Galateanu
Octav Ginghină
Georgios Georgiadis
Charalampos Mamoulakis
author_sort Irina Bondoc
collection DOAJ
description Ulcerative colitis (UC) is a chronic immune-mediated inflammatory disorder affecting the colon, which displays an increasing incidence worldwide and is characterized by symptoms of rectal inflammation such as rectal bleeding, tenesmus and multiple stools daily. The diagnosis of UC is not easy to establish, therefor an overall interpretation of the clinical manifestations together with the results of the laboratory tests, lower gastrointestinal endoscopic examination (colonoscopy) and histopathology examination findings are advisable. The choice of therapy for ulcerative colitis is based on activity, severity and extension of lesions and may include oral, systemic and topic therapy, as well as surgery. Patients with ulcerative colitis are generally immunocompromised predisposed to opportunistic infections. We present the case of a male aged 70 years diagnosed with ulcerative colitis with insidious evolution under systemic treatment, complicated with Fournier’s gangrene which is a very rare complication of ulcerative colitis that should be kept in mind. A multidisciplinary approach including urologists and colorectal surgeons is the key to define best individualized management.
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spelling doaj-art-69d5f3a6ce6a40838b6a9daf24e57fc32025-08-20T02:49:47ZengEuropean PublishingPublic Health and Toxicology2732-89292023-01-01311710.18332/pht/159116159116Ulcerative colitis complicated with Fournier’s gangrene: A case reportIrina Bondoc0Marius Zamfir1Mara Mardare2Andrei Văcărașu3Alin Burlacu4Leila Ali5Ariana Hudita6Bianca Galateanu7https://orcid.org/0000-0001-8093-1750Octav Ginghină8Georgios Georgiadis9Charalampos Mamoulakis10Surgery 3 Department, Institute of Oncology ‘Prof. Dr. A. Trestioreanu’, Bucharest, RomaniaSurgery 3 Department, Institute of Oncology ‘Prof. Dr. A. Trestioreanu’, Bucharest, RomaniaSurgery 3 Department, Institute of Oncology ‘Prof. Dr. A. Trestioreanu’, Bucharest, RomaniaSurgery 3 Department, Institute of Oncology ‘Prof. Dr. A. Trestioreanu’, Bucharest, RomaniaSurgery 3 Department, Institute of Oncology ‘Prof. Dr. A. Trestioreanu’, Bucharest, RomaniaGeneral Surgery Department, Emergency Clinical Hospital ‘Sf. Ioan’, Bucharest, RomaniaDepartment of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, RomaniaDepartment of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, RomaniaSurgery 3 Department, Institute of Oncology ‘Prof. Dr. A. Trestioreanu’, Bucharest, RomaniaDepartment of Urology, University General Hospital of Heraklion, Heraklion, GreeceDepartment of Urology, University General Hospital of Heraklion, Heraklion, GreeceUlcerative colitis (UC) is a chronic immune-mediated inflammatory disorder affecting the colon, which displays an increasing incidence worldwide and is characterized by symptoms of rectal inflammation such as rectal bleeding, tenesmus and multiple stools daily. The diagnosis of UC is not easy to establish, therefor an overall interpretation of the clinical manifestations together with the results of the laboratory tests, lower gastrointestinal endoscopic examination (colonoscopy) and histopathology examination findings are advisable. The choice of therapy for ulcerative colitis is based on activity, severity and extension of lesions and may include oral, systemic and topic therapy, as well as surgery. Patients with ulcerative colitis are generally immunocompromised predisposed to opportunistic infections. We present the case of a male aged 70 years diagnosed with ulcerative colitis with insidious evolution under systemic treatment, complicated with Fournier’s gangrene which is a very rare complication of ulcerative colitis that should be kept in mind. A multidisciplinary approach including urologists and colorectal surgeons is the key to define best individualized management.https://www.publichealthtoxicology.com/Ulcerative-colitis-complicated-with-Fournier-s-gangrene-nA-case-report,159116,0,2.htmlulcerative colitisperianal fistulaclostridium difficilefournier’s gangrene
spellingShingle Irina Bondoc
Marius Zamfir
Mara Mardare
Andrei Văcărașu
Alin Burlacu
Leila Ali
Ariana Hudita
Bianca Galateanu
Octav Ginghină
Georgios Georgiadis
Charalampos Mamoulakis
Ulcerative colitis complicated with Fournier’s gangrene: A case report
Public Health and Toxicology
ulcerative colitis
perianal fistula
clostridium difficile
fournier’s gangrene
title Ulcerative colitis complicated with Fournier’s gangrene: A case report
title_full Ulcerative colitis complicated with Fournier’s gangrene: A case report
title_fullStr Ulcerative colitis complicated with Fournier’s gangrene: A case report
title_full_unstemmed Ulcerative colitis complicated with Fournier’s gangrene: A case report
title_short Ulcerative colitis complicated with Fournier’s gangrene: A case report
title_sort ulcerative colitis complicated with fournier s gangrene a case report
topic ulcerative colitis
perianal fistula
clostridium difficile
fournier’s gangrene
url https://www.publichealthtoxicology.com/Ulcerative-colitis-complicated-with-Fournier-s-gangrene-nA-case-report,159116,0,2.html
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