Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patients
A prospective randomized observational study was conducted in cohorts of vaccinated and unvaccinated patients hospitalized in one of the Moscow hospitals and diagnozed with COVID-19 in the period from 06.23.2021 to 01.05.2022.The purpose of the study was to identify the epidemiological features of C...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2024-04-01
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| Series: | Журнал инфектологии |
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| Online Access: | https://journal.niidi.ru/jofin/article/view/1603 |
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| author | M. P. Kostinov C. Zhang I. A. Khrapunova S. R. Raicic A. S. Pechenik V. A. Utkin M. N. Loktionova A. V. Linok E. G. Simonova V. A. Brazhnik |
| author_facet | M. P. Kostinov C. Zhang I. A. Khrapunova S. R. Raicic A. S. Pechenik V. A. Utkin M. N. Loktionova A. V. Linok E. G. Simonova V. A. Brazhnik |
| author_sort | M. P. Kostinov |
| collection | DOAJ |
| description | A prospective randomized observational study was conducted in cohorts of vaccinated and unvaccinated patients hospitalized in one of the Moscow hospitals and diagnozed with COVID-19 in the period from 06.23.2021 to 01.05.2022.The purpose of the study was to identify the epidemiological features of COVID-19 in vaccinated people and to present scientifically based data on the need for vaccination and its importance in stopping the epidemic process.Materials and Methods. The samples were studied in comparison for a number of indicators: age, clinical condition at admission, the presence and number of concomitant systemic chronic diseases as well as disease outcomes.Results. It was proven that the risk of COVID-19 morbidity in vaccinated people decreased by 1.5 times, mortality by 1.5 times, and hospitalization due to the severity of the condition by 3.1 times. The mortality risk among vaccinated patients shifted to older age (76.9 years), while among unvaccinated patients, the mortality risk was higher for older people (73.7 years), which indicates an increase in life expectancy of vaccinated people. |
| format | Article |
| id | doaj-art-69d4cc77f8e441bfa41c62f393920f1f |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2024-04-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-69d4cc77f8e441bfa41c62f393920f1f2025-08-20T03:38:30ZrusJournal InfectologyЖурнал инфектологии2072-67322024-04-01161152110.22625/2072-6732-2024-16-1-15-211130Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patientsM. P. Kostinov0C. Zhang1I. A. Khrapunova2S. R. Raicic3A. S. Pechenik4V. A. Utkin5M. N. Loktionova6A. V. Linok7E. G. Simonova8V. A. Brazhnik9First Moscow State Medical University named after I.M. Sechenov; Research Institute of Vaccines and Sera named after I.I. MechnikovFirst Moscow State Medical University named after I.M. SechenovFirst Moscow State Medical University named after I.M. Sechenov; Central Research Institute of EpidemiologyFirst Moscow State Medical University named after I.M. SechenovCity Clinical Hospital No. 29 named after N.E. BaumanCenter for biomedical technologies of the North-Caucasian Federal Research and Clinical CenterFirst Moscow State Medical University named after I.M. SechenovFirst Moscow State Medical University named after I.M. SechenovFirst Moscow State Medical University named after I.M. SechenovCity Clinical Hospital No. 29 named after N.E. BaumanA prospective randomized observational study was conducted in cohorts of vaccinated and unvaccinated patients hospitalized in one of the Moscow hospitals and diagnozed with COVID-19 in the period from 06.23.2021 to 01.05.2022.The purpose of the study was to identify the epidemiological features of COVID-19 in vaccinated people and to present scientifically based data on the need for vaccination and its importance in stopping the epidemic process.Materials and Methods. The samples were studied in comparison for a number of indicators: age, clinical condition at admission, the presence and number of concomitant systemic chronic diseases as well as disease outcomes.Results. It was proven that the risk of COVID-19 morbidity in vaccinated people decreased by 1.5 times, mortality by 1.5 times, and hospitalization due to the severity of the condition by 3.1 times. The mortality risk among vaccinated patients shifted to older age (76.9 years), while among unvaccinated patients, the mortality risk was higher for older people (73.7 years), which indicates an increase in life expectancy of vaccinated people.https://journal.niidi.ru/jofin/article/view/1603covid-19mortalityrisk groupsrisk factorsvaccination |
| spellingShingle | M. P. Kostinov C. Zhang I. A. Khrapunova S. R. Raicic A. S. Pechenik V. A. Utkin M. N. Loktionova A. V. Linok E. G. Simonova V. A. Brazhnik Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patients Журнал инфектологии covid-19 mortality risk groups risk factors vaccination |
| title | Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patients |
| title_full | Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patients |
| title_fullStr | Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patients |
| title_full_unstemmed | Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patients |
| title_short | Possible causes of morbidity and adverse outcomes of COVID-19 in vaccinated elderly patients |
| title_sort | possible causes of morbidity and adverse outcomes of covid 19 in vaccinated elderly patients |
| topic | covid-19 mortality risk groups risk factors vaccination |
| url | https://journal.niidi.ru/jofin/article/view/1603 |
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