Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review

Malignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are extremely rare. Published data on primary pulmonary malignant melanomas are limited. Up to now 40 relevant cases have been reported in the English literature. Herein, we report a case of...

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Main Authors: Christos Kyriakopoulos, George Zarkavelis, Artemis Andrianopoulou, Alexandra Papoudou-Bai, Dimitrios Stefanou, Stergios Boussios, George Pentheroudakis
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2017/8654326
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author Christos Kyriakopoulos
George Zarkavelis
Artemis Andrianopoulou
Alexandra Papoudou-Bai
Dimitrios Stefanou
Stergios Boussios
George Pentheroudakis
author_facet Christos Kyriakopoulos
George Zarkavelis
Artemis Andrianopoulou
Alexandra Papoudou-Bai
Dimitrios Stefanou
Stergios Boussios
George Pentheroudakis
author_sort Christos Kyriakopoulos
collection DOAJ
description Malignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are extremely rare. Published data on primary pulmonary malignant melanomas are limited. Up to now 40 relevant cases have been reported in the English literature. Herein, we report a case of a 56-year-old female patient who presented with intracranial metastases due to primary pulmonary melanoma. She underwent bronchoscopy and died 5 months after the initial diagnosis despite the administered biochemotherapy and subsequent immunotherapy. To establish the diagnosis of primary pulmonary malignant melanoma, any extrapulmonary origin was excluded by detailed examination and radiographic imaging. Moreover, an extensive review of the literature regarding this rare entity has been performed.
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institution Kabale University
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publishDate 2017-01-01
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series Case Reports in Oncological Medicine
spelling doaj-art-69cc4e05c70143189918ee8ecaad92f12025-08-20T03:34:08ZengWileyCase Reports in Oncological Medicine2090-67062090-67142017-01-01201710.1155/2017/86543268654326Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature ReviewChristos Kyriakopoulos0George Zarkavelis1Artemis Andrianopoulou2Alexandra Papoudou-Bai3Dimitrios Stefanou4Stergios Boussios5George Pentheroudakis6Department of Pulmonary Medicine, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, GreeceDepartment of Medical Oncology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, GreeceDepartment of Radiology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, GreeceDepartment of Pathology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, GreeceDepartment of Pathology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, GreeceDepartment of Medical Oncology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, GreeceDepartment of Medical Oncology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, GreeceMalignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are extremely rare. Published data on primary pulmonary malignant melanomas are limited. Up to now 40 relevant cases have been reported in the English literature. Herein, we report a case of a 56-year-old female patient who presented with intracranial metastases due to primary pulmonary melanoma. She underwent bronchoscopy and died 5 months after the initial diagnosis despite the administered biochemotherapy and subsequent immunotherapy. To establish the diagnosis of primary pulmonary malignant melanoma, any extrapulmonary origin was excluded by detailed examination and radiographic imaging. Moreover, an extensive review of the literature regarding this rare entity has been performed.http://dx.doi.org/10.1155/2017/8654326
spellingShingle Christos Kyriakopoulos
George Zarkavelis
Artemis Andrianopoulou
Alexandra Papoudou-Bai
Dimitrios Stefanou
Stergios Boussios
George Pentheroudakis
Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review
Case Reports in Oncological Medicine
title Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review
title_full Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review
title_fullStr Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review
title_full_unstemmed Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review
title_short Primary Pulmonary Malignant Melanoma: Report of an Important Entity and Literature Review
title_sort primary pulmonary malignant melanoma report of an important entity and literature review
url http://dx.doi.org/10.1155/2017/8654326
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