Umbilical cord vascular thrombosis: literature review and two clinical cases
Thrombosis of the umbilical cord vessels is a rare complication of pregnancy, combined with a high level of perinatal morbidity and mortality. Anomalies of vascular attachment (velamentous attachment), pathology of the umbilical cord (hyperspiralization, short or long umbilical cord), intrauterine i...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IRBIS LLC
2022-03-01
|
| Series: | Акушерство, гинекология и репродукция |
| Subjects: | |
| Online Access: | https://www.gynecology.su/jour/article/view/1245 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849395506566922240 |
|---|---|
| author | E. Iu. Iupatov T. E. Kurmanbaev I. R. Galimova A. T. Khaertdinov R. R. Mukhametova A. L. Mirolyubov D. N. Ablaeva A. M. Khromova M. I. Timerzyanov M. D. Leonova |
| author_facet | E. Iu. Iupatov T. E. Kurmanbaev I. R. Galimova A. T. Khaertdinov R. R. Mukhametova A. L. Mirolyubov D. N. Ablaeva A. M. Khromova M. I. Timerzyanov M. D. Leonova |
| author_sort | E. Iu. Iupatov |
| collection | DOAJ |
| description | Thrombosis of the umbilical cord vessels is a rare complication of pregnancy, combined with a high level of perinatal morbidity and mortality. Anomalies of vascular attachment (velamentous attachment), pathology of the umbilical cord (hyperspiralization, short or long umbilical cord), intrauterine infections, maternal diabetes mellitus and preeclampsia as well as meconium found in the amniotic fluid are among the risk factors of developing thrombosis in the umbilical cord vessels. Here we present two clinical observations of umbilical vein thrombosis at full-term pregnancy. In both cases, during pregnancy and childbirth, no signs of umbilical cord pathology were found according to cardiotocography and Doppler ultrasound; despite this, the children were born in hypoxic state. Both newborns were transferred to the second stage of treatment due to suspected intrauterine pneumonia. Velamentous attachment, intrauterine infections as well as meconium found in the amniotic fluid were the risk factors of developing umbilical vein thrombosis described in case 1 and case 2, respectively. During pregnancy, both female patients suffered from clinically confirmed novel coronavirus infection (COVID-19) and contacted patients with COVID-19 in the third trimester of gestation. It is likely that endothelial damage caused by the novel coronavirus SARS-CoV-2 was one of the risk factors for the development of umbilical vein thrombosis, but this issue requires to be further explored. |
| format | Article |
| id | doaj-art-69cb3ef5df0c4cdf8ad37df08195cf74 |
| institution | Kabale University |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2022-03-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-69cb3ef5df0c4cdf8ad37df08195cf742025-08-20T03:39:36ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942022-03-01161818910.17749/2313-7347/ob.gyn.rep.2021.260711Umbilical cord vascular thrombosis: literature review and two clinical casesE. Iu. Iupatov0T. E. Kurmanbaev1I. R. Galimova2A. T. Khaertdinov3R. R. Mukhametova4A. L. Mirolyubov5D. N. Ablaeva6A. M. Khromova7M. I. Timerzyanov8M. D. Leonova9Kazan State Medical Academy – Branch of Russian Medical Academy of Continuing Professional Education, Health Ministry of Russian Federation; Kazan (Volga Region) Federal UniversityKirov Military Medical Academy, Ministry of Defense of Russian FederationKazan (Volga Region) Federal UniversityKazan (Volga Region) Federal UniversityKazan (Volga Region) Federal UniversityKazan (Volga Region) Federal UniversityKazan (Volga Region) Federal UniversityKazan State Medical Academy – Branch of Russian Medical Academy of Continuing Professional Education, Health Ministry of Russian Federation; Kazan (Volga Region) Federal UniversityKazan State Medical Academy – Branch of Russian Medical Academy of Continuing Professional Education, Health Ministry of Russian Federation; Kazan (Volga Region) Federal UniversityMaternity Hospital № 13Thrombosis of the umbilical cord vessels is a rare complication of pregnancy, combined with a high level of perinatal morbidity and mortality. Anomalies of vascular attachment (velamentous attachment), pathology of the umbilical cord (hyperspiralization, short or long umbilical cord), intrauterine infections, maternal diabetes mellitus and preeclampsia as well as meconium found in the amniotic fluid are among the risk factors of developing thrombosis in the umbilical cord vessels. Here we present two clinical observations of umbilical vein thrombosis at full-term pregnancy. In both cases, during pregnancy and childbirth, no signs of umbilical cord pathology were found according to cardiotocography and Doppler ultrasound; despite this, the children were born in hypoxic state. Both newborns were transferred to the second stage of treatment due to suspected intrauterine pneumonia. Velamentous attachment, intrauterine infections as well as meconium found in the amniotic fluid were the risk factors of developing umbilical vein thrombosis described in case 1 and case 2, respectively. During pregnancy, both female patients suffered from clinically confirmed novel coronavirus infection (COVID-19) and contacted patients with COVID-19 in the third trimester of gestation. It is likely that endothelial damage caused by the novel coronavirus SARS-CoV-2 was one of the risk factors for the development of umbilical vein thrombosis, but this issue requires to be further explored.https://www.gynecology.su/jour/article/view/1245pregnancythrombosis of umbilical cord vesselsnovel coronavirus infectioncovid-19sars-cov-2velamentous attachment of umbilical cord vesselsumbilical vein thrombosis |
| spellingShingle | E. Iu. Iupatov T. E. Kurmanbaev I. R. Galimova A. T. Khaertdinov R. R. Mukhametova A. L. Mirolyubov D. N. Ablaeva A. M. Khromova M. I. Timerzyanov M. D. Leonova Umbilical cord vascular thrombosis: literature review and two clinical cases Акушерство, гинекология и репродукция pregnancy thrombosis of umbilical cord vessels novel coronavirus infection covid-19 sars-cov-2 velamentous attachment of umbilical cord vessels umbilical vein thrombosis |
| title | Umbilical cord vascular thrombosis: literature review and two clinical cases |
| title_full | Umbilical cord vascular thrombosis: literature review and two clinical cases |
| title_fullStr | Umbilical cord vascular thrombosis: literature review and two clinical cases |
| title_full_unstemmed | Umbilical cord vascular thrombosis: literature review and two clinical cases |
| title_short | Umbilical cord vascular thrombosis: literature review and two clinical cases |
| title_sort | umbilical cord vascular thrombosis literature review and two clinical cases |
| topic | pregnancy thrombosis of umbilical cord vessels novel coronavirus infection covid-19 sars-cov-2 velamentous attachment of umbilical cord vessels umbilical vein thrombosis |
| url | https://www.gynecology.su/jour/article/view/1245 |
| work_keys_str_mv | AT eiuiupatov umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT tekurmanbaev umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT irgalimova umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT atkhaertdinov umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT rrmukhametova umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT almirolyubov umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT dnablaeva umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT amkhromova umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT mitimerzyanov umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases AT mdleonova umbilicalcordvascularthrombosisliteraturereviewandtwoclinicalcases |