Granuloma Multiforme: A Rare Granulomatous Disease
Granuloma Multiforme (GM) is a reactive skin disorder with annular lesion and focal necrobiosis. It was first described in Nigeria (Africa), since than it was mostly described from various regions of Africa where leprosy was endemic. Outside Africa, this disease is rarely reported. Till 2016 only fi...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/5485034 |
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| author | Yogesh Poudyal Anita Shah |
| author_facet | Yogesh Poudyal Anita Shah |
| author_sort | Yogesh Poudyal |
| collection | DOAJ |
| description | Granuloma Multiforme (GM) is a reactive skin disorder with annular lesion and focal necrobiosis. It was first described in Nigeria (Africa), since than it was mostly described from various regions of Africa where leprosy was endemic. Outside Africa, this disease is rarely reported. Till 2016 only five cases were reported from India. This is the second case report from Nepal. A fifty-nine-year-old female, farmer by occupation, presented with annular and polycyclic plaques with elevated beaded border for one year. It was distributed over upper trunk, lower back, and arms, and was mildly pruritic. Histopathologically, loss of elastic fibres at focal area of upper dermis, with elastic fibres engulfed histiocytes were noted. GM was mostly noted from leprosy endemic areas of Africa. Clinically, it is very difficult to distinguish from granuloma annulare. This report adds the number of GM occurrence in Asia especially from area where leprosy is still prevalent. This report also emphasizes in resource poor settings where most diagnosis is made clinically, the granuloma annulare should be looked for very carefully in order not to miss GM. |
| format | Article |
| id | doaj-art-69b6b717adaf4cb1ba9f32e9e6443cfe |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-69b6b717adaf4cb1ba9f32e9e6443cfe2025-02-03T07:26:10ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712019-01-01201910.1155/2019/54850345485034Granuloma Multiforme: A Rare Granulomatous DiseaseYogesh Poudyal0Anita Shah1Sarnath Skin Centre, Shanti Path, Bhairahawa 32900, NepalDepartment of Pathology, Universal College of Medical Sciences-Teaching Hospital, Ranigaon, Bhairahawa 32900, NepalGranuloma Multiforme (GM) is a reactive skin disorder with annular lesion and focal necrobiosis. It was first described in Nigeria (Africa), since than it was mostly described from various regions of Africa where leprosy was endemic. Outside Africa, this disease is rarely reported. Till 2016 only five cases were reported from India. This is the second case report from Nepal. A fifty-nine-year-old female, farmer by occupation, presented with annular and polycyclic plaques with elevated beaded border for one year. It was distributed over upper trunk, lower back, and arms, and was mildly pruritic. Histopathologically, loss of elastic fibres at focal area of upper dermis, with elastic fibres engulfed histiocytes were noted. GM was mostly noted from leprosy endemic areas of Africa. Clinically, it is very difficult to distinguish from granuloma annulare. This report adds the number of GM occurrence in Asia especially from area where leprosy is still prevalent. This report also emphasizes in resource poor settings where most diagnosis is made clinically, the granuloma annulare should be looked for very carefully in order not to miss GM.http://dx.doi.org/10.1155/2019/5485034 |
| spellingShingle | Yogesh Poudyal Anita Shah Granuloma Multiforme: A Rare Granulomatous Disease Case Reports in Dermatological Medicine |
| title | Granuloma Multiforme: A Rare Granulomatous Disease |
| title_full | Granuloma Multiforme: A Rare Granulomatous Disease |
| title_fullStr | Granuloma Multiforme: A Rare Granulomatous Disease |
| title_full_unstemmed | Granuloma Multiforme: A Rare Granulomatous Disease |
| title_short | Granuloma Multiforme: A Rare Granulomatous Disease |
| title_sort | granuloma multiforme a rare granulomatous disease |
| url | http://dx.doi.org/10.1155/2019/5485034 |
| work_keys_str_mv | AT yogeshpoudyal granulomamultiformeararegranulomatousdisease AT anitashah granulomamultiformeararegranulomatousdisease |