Single-cell and machine learning integration reveals ferroptosis-driven immune landscapes for melanoma stratification

Single-cell and machine learning integration reveals ferroptosis-driven immune landscapes for melanoma stratification

BackgroundFerroptosis, a regulated form of cell death, has emerged as a critical modulator of melanoma's tumor progression and immune evasion. However, its integration with the tumor immune microenvironment (TME) and clinical prognostication remains underexplored. This study aims to construct a...

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Bibliographic Details
Main Authors: Lei Wang, Xueying Jin, Yuchen Wu, Runing Qiu, Jianfang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
ferroptosis
melanoma
immune microenvironment
single-cell RNA sequencing
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1624691/full
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