SIRT5-mediated desuccinylation of the porcine deltacoronavirus M protein drives pexophagy to enhance viral proliferation.

SIRT5-mediated desuccinylation of the porcine deltacoronavirus M protein drives pexophagy to enhance viral proliferation.

Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus capable of infecting various animal species, including humans. In this study, we explored the roles of sirtuins (SIRTs), a conserved family of protein deacylases and mono-adenosine diphosphate-ribosyltransferases, in PDCoV...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhuang Li, Wenbing Tang, Yinan Lai, Chaoqun Chen, Puxian Fang, Yanrong Zhou, Liurong Fang, Shaobo Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013163
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items