Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient
A description of a clinical case of a severe, protracted course of coronavirus infection (COVID-19) in a patient with advanced stage HIV infection, characterized by prolonged release of the SARS-CoV-2 virus and the formation of pulmonary fibrosis against the background of an active viral infection,...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2024-04-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/1617 |
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| author | M. A. Savchenko V. B. Musatov D. A. Gusev V. A. Cinzerling |
| author_facet | M. A. Savchenko V. B. Musatov D. A. Gusev V. A. Cinzerling |
| author_sort | M. A. Savchenko |
| collection | DOAJ |
| description | A description of a clinical case of a severe, protracted course of coronavirus infection (COVID-19) in a patient with advanced stage HIV infection, characterized by prolonged release of the SARS-CoV-2 virus and the formation of pulmonary fibrosis against the background of an active viral infection, is presented. COVID-19 infection occurred in an immunosuppressed patient without ART. During the period of inpatient treatment, a comprehensive examination was carried out to exclude HIV-associated lung lesions; no evidence of viral, fungal, or bacterial pathology was obtained; mycobacterial infections were also excluded. Despite two courses of antiviral therapy, the use of anti-Covid plasma and complex pathogenetic therapy, persistence of SARS-CoV-2 replication was observed for eight months, with a steady progression of the disease, ending in death. |
| format | Article |
| id | doaj-art-69a57f6a846b4565ae5c6f4df957bb51 |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2024-04-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-69a57f6a846b4565ae5c6f4df957bb512025-08-20T03:38:30ZrusJournal InfectologyЖурнал инфектологии2072-67322024-04-01161879310.22625/2072-6732-2024-16-1-87-931140Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patientM. A. Savchenko0V. B. Musatov1D. A. Gusev2V. A. Cinzerling3Clinical Infectious Disease Hospital named after S.P. BotkinClinical Infectious Disease Hospital named after S.P. Botkin; Saint-Petersburg State UniversityClinical Infectious Disease Hospital named after S.P. Botkin; National Medical Research Centre named after V.A. AlmazovClinical Infectious Disease Hospital named after S.P. Botkin; National Medical Research Centre named after V.A. AlmazovA description of a clinical case of a severe, protracted course of coronavirus infection (COVID-19) in a patient with advanced stage HIV infection, characterized by prolonged release of the SARS-CoV-2 virus and the formation of pulmonary fibrosis against the background of an active viral infection, is presented. COVID-19 infection occurred in an immunosuppressed patient without ART. During the period of inpatient treatment, a comprehensive examination was carried out to exclude HIV-associated lung lesions; no evidence of viral, fungal, or bacterial pathology was obtained; mycobacterial infections were also excluded. Despite two courses of antiviral therapy, the use of anti-Covid plasma and complex pathogenetic therapy, persistence of SARS-CoV-2 replication was observed for eight months, with a steady progression of the disease, ending in death.https://journal.niidi.ru/jofin/article/view/1617coronavirus infection covid-19pneumofibrosispulmonary fibrosishivmorphological picture |
| spellingShingle | M. A. Savchenko V. B. Musatov D. A. Gusev V. A. Cinzerling Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient Журнал инфектологии coronavirus infection covid-19 pneumofibrosis pulmonary fibrosis hiv morphological picture |
| title | Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient |
| title_full | Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient |
| title_fullStr | Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient |
| title_full_unstemmed | Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient |
| title_short | Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient |
| title_sort | prolonged course of novel coronavirus infection covid 19 with the formation of pulmonary fibrosis in an hiv infected patient |
| topic | coronavirus infection covid-19 pneumofibrosis pulmonary fibrosis hiv morphological picture |
| url | https://journal.niidi.ru/jofin/article/view/1617 |
| work_keys_str_mv | AT masavchenko prolongedcourseofnovelcoronavirusinfectioncovid19withtheformationofpulmonaryfibrosisinanhivinfectedpatient AT vbmusatov prolongedcourseofnovelcoronavirusinfectioncovid19withtheformationofpulmonaryfibrosisinanhivinfectedpatient AT dagusev prolongedcourseofnovelcoronavirusinfectioncovid19withtheformationofpulmonaryfibrosisinanhivinfectedpatient AT vacinzerling prolongedcourseofnovelcoronavirusinfectioncovid19withtheformationofpulmonaryfibrosisinanhivinfectedpatient |