Galleria mellonella as a drug discovery model to study oxidative stress

Galleria mellonella as a drug discovery model to study oxidative stress

Abstract Biological systems are equipped with endogenous antioxidant defence mechanisms against reactive oxygen species (ROS). Accumulation of ROS usually overwhelms this, creating pathologic effects. Oxidative toxicity has been reported as a causative factor in neurodegenerative diseases, cancer an...

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Bibliographic Details
Main Authors: Fred Jonathan Edzeamey, Zenouska Ramchunder, Ronan R. McCarthy, Sara Anjomani Virmouni
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Galleria mellonella
Oxidative toxicity
Fibroblast cells
Antioxidants
In vivo
In vitro
Online Access:https://doi.org/10.1038/s41598-025-99337-6
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