Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes
The hypothalamic neuropeptides kisspeptin-10 (KiSS-10), neurokinin B (NKB), and dynorphin A (Dyn A) play roles in the endocrine regulation of the hypothalamic–pituitary–ovarian (HPO) axis in puberty. Livestock’s timely attainment of sexual maturity increases reproductive efficiency and raises profit...
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| Format: | Article |
| Language: | English |
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Sciendo
2025-01-01
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| Series: | Journal of Veterinary Research |
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| Online Access: | https://doi.org/10.2478/jvetres-2025-0003 |
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| author | Szysiak Natalia Kosior-Korzecka Urszula Longo Vincenzo Patkowski Krzysztof Greguła-Kania Monika Nowakiewicz Aneta Bochniarz Mariola Junkuszew Andrzej |
| author_facet | Szysiak Natalia Kosior-Korzecka Urszula Longo Vincenzo Patkowski Krzysztof Greguła-Kania Monika Nowakiewicz Aneta Bochniarz Mariola Junkuszew Andrzej |
| author_sort | Szysiak Natalia |
| collection | DOAJ |
| description | The hypothalamic neuropeptides kisspeptin-10 (KiSS-10), neurokinin B (NKB), and dynorphin A (Dyn A) play roles in the endocrine regulation of the hypothalamic–pituitary–ovarian (HPO) axis in puberty. Livestock’s timely attainment of sexual maturity increases reproductive efficiency and raises profitability. The pituitary relationship between these neuropeptides and gonadotropins in puberty in ewes being undercharacterised. The aim of the study was to analyse their direct effect on gonadotropin secretion by pituitary cells isolated from pubescent ewes. |
| format | Article |
| id | doaj-art-6995c857a0e947998ff2e6c4d92ee3c3 |
| institution | DOAJ |
| issn | 2450-8608 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Veterinary Research |
| spelling | doaj-art-6995c857a0e947998ff2e6c4d92ee3c32025-08-20T03:10:04ZengSciendoJournal of Veterinary Research2450-86082025-01-0169112112910.2478/jvetres-2025-0003Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewesSzysiak Natalia0Kosior-Korzecka Urszula1Longo Vincenzo2Patkowski Krzysztof3Greguła-Kania Monika4Nowakiewicz Aneta5Bochniarz Mariola6Junkuszew Andrzej7Sub-Department of Pathophysiology, Lublin, PolandSub-Department of Pathophysiology, Lublin, PolandNational Research Council, Institute of Agricultural Biology and Biotechnology, Research Unit of Pisa, 56124Pisa, ItalyDepartment of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950Lublin, PolandDepartment of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950Lublin, PolandSub-Department of Veterinary Microbiology, Department of Preclinical Veterinary Sciences, Faculty of Veterinary Medicine, Lublin, PolandSub-Department of Veterinary Microbiology, Department of Preclinical Veterinary Sciences, Faculty of Veterinary Medicine, Lublin, PolandDepartment of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950Lublin, PolandThe hypothalamic neuropeptides kisspeptin-10 (KiSS-10), neurokinin B (NKB), and dynorphin A (Dyn A) play roles in the endocrine regulation of the hypothalamic–pituitary–ovarian (HPO) axis in puberty. Livestock’s timely attainment of sexual maturity increases reproductive efficiency and raises profitability. The pituitary relationship between these neuropeptides and gonadotropins in puberty in ewes being undercharacterised. The aim of the study was to analyse their direct effect on gonadotropin secretion by pituitary cells isolated from pubescent ewes.https://doi.org/10.2478/jvetres-2025-0003neurokinin bdynorphin akisspeptingonadotropinpuberty |
| spellingShingle | Szysiak Natalia Kosior-Korzecka Urszula Longo Vincenzo Patkowski Krzysztof Greguła-Kania Monika Nowakiewicz Aneta Bochniarz Mariola Junkuszew Andrzej Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes Journal of Veterinary Research neurokinin b dynorphin a kisspeptin gonadotropin puberty |
| title | Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes |
| title_full | Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes |
| title_fullStr | Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes |
| title_full_unstemmed | Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes |
| title_short | Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes |
| title_sort | influence of neurokinin b dynorphin a and kisspeptin 10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes |
| topic | neurokinin b dynorphin a kisspeptin gonadotropin puberty |
| url | https://doi.org/10.2478/jvetres-2025-0003 |
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