Correction by Laennec of chronic iron overload liver, kidneys and brain

The results of experimental investigations of the effects of Laennec on chronic iron overload. Long-term (2 weeks) application of iron sulfate or iron polymaltose complex composition caused chronic iron overload (hemosiderosis). The liver and kidneys is more pronounced when using iron sulfate and a...

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Main Authors: O. A. Nazarenko, O. A. Gromova, T. R. Grishina, I. Yu. Torshin, V. I. Demidov, I. K. Tomilova, E. L. Aleksakhina, I. V. Gogoleva
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2017-03-01
Series:Фармакокинетика и Фармакодинамика
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Online Access:https://www.pharmacokinetica.ru/jour/article/view/18
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author O. A. Nazarenko
O. A. Gromova
T. R. Grishina
I. Yu. Torshin
V. I. Demidov
I. K. Tomilova
E. L. Aleksakhina
I. V. Gogoleva
author_facet O. A. Nazarenko
O. A. Gromova
T. R. Grishina
I. Yu. Torshin
V. I. Demidov
I. K. Tomilova
E. L. Aleksakhina
I. V. Gogoleva
author_sort O. A. Nazarenko
collection DOAJ
description The results of experimental investigations of the effects of Laennec on chronic iron overload. Long-term (2 weeks) application of iron sulfate or iron polymaltose complex composition caused chronic iron overload (hemosiderosis). The liver and kidneys is more pronounced when using iron sulfate and a few less - when using polymaltose complex. Laennec decreased the damage of hepatocytes (decreased ALT levels). According to histological analysis application Laennec reduced iron deposition in the liver and kidneys and completely prevented the formation of iron deposits in the brain.
format Article
id doaj-art-698e0f979ceb4f268f9a6eac65b60aea
institution Kabale University
issn 2587-7836
2686-8830
language Russian
publishDate 2017-03-01
publisher LLC “Publisher OKI”
record_format Article
series Фармакокинетика и Фармакодинамика
spelling doaj-art-698e0f979ceb4f268f9a6eac65b60aea2025-08-20T03:57:48ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302017-03-0102394417Correction by Laennec of chronic iron overload liver, kidneys and brainO. A. Nazarenko0O. A. Gromova1T. R. Grishina2I. Yu. Torshin3V. I. Demidov4I. K. Tomilova5E. L. Aleksakhina6I. V. Gogoleva7FGBOU IN «Ivanovo State Medical Academy» Russian Ministry of HealthFGBOU IN «Ivanovo State Medical Academy» Russian Ministry of HealthFGBOU IN «Ivanovo State Medical Academy» Russian Ministry of HealthFGBOU IN «Moscow Institute of Physics and Technology»FGBOU IN «Ivanovo State Medical Academy» Russian Ministry of HealthFGBOU IN «Ivanovo State Medical Academy» Russian Ministry of HealthFGBOU IN «Ivanovo State Medical Academy» Russian Ministry of HealthFGBOU IN «Ivanovo State Medical Academy» Russian Ministry of HealthThe results of experimental investigations of the effects of Laennec on chronic iron overload. Long-term (2 weeks) application of iron sulfate or iron polymaltose complex composition caused chronic iron overload (hemosiderosis). The liver and kidneys is more pronounced when using iron sulfate and a few less - when using polymaltose complex. Laennec decreased the damage of hepatocytes (decreased ALT levels). According to histological analysis application Laennec reduced iron deposition in the liver and kidneys and completely prevented the formation of iron deposits in the brain.https://www.pharmacokinetica.ru/jour/article/view/18гемосидерозболезни перегрузки железомсульфат железаполимальтозные комплексы железалаеннекинсулиноподобный фактор роста 1hemosiderosisa disease of iron overloadiron sulfatepolymaltose iron complexlaennecinsulin-like growth factor 1
spellingShingle O. A. Nazarenko
O. A. Gromova
T. R. Grishina
I. Yu. Torshin
V. I. Demidov
I. K. Tomilova
E. L. Aleksakhina
I. V. Gogoleva
Correction by Laennec of chronic iron overload liver, kidneys and brain
Фармакокинетика и Фармакодинамика
гемосидероз
болезни перегрузки железом
сульфат железа
полимальтозные комплексы железа
лаеннек
инсулиноподобный фактор роста 1
hemosiderosis
a disease of iron overload
iron sulfate
polymaltose iron complex
laennec
insulin-like growth factor 1
title Correction by Laennec of chronic iron overload liver, kidneys and brain
title_full Correction by Laennec of chronic iron overload liver, kidneys and brain
title_fullStr Correction by Laennec of chronic iron overload liver, kidneys and brain
title_full_unstemmed Correction by Laennec of chronic iron overload liver, kidneys and brain
title_short Correction by Laennec of chronic iron overload liver, kidneys and brain
title_sort correction by laennec of chronic iron overload liver kidneys and brain
topic гемосидероз
болезни перегрузки железом
сульфат железа
полимальтозные комплексы железа
лаеннек
инсулиноподобный фактор роста 1
hemosiderosis
a disease of iron overload
iron sulfate
polymaltose iron complex
laennec
insulin-like growth factor 1
url https://www.pharmacokinetica.ru/jour/article/view/18
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AT iyutorshin correctionbylaennecofchronicironoverloadliverkidneysandbrain
AT videmidov correctionbylaennecofchronicironoverloadliverkidneysandbrain
AT iktomilova correctionbylaennecofchronicironoverloadliverkidneysandbrain
AT elaleksakhina correctionbylaennecofchronicironoverloadliverkidneysandbrain
AT ivgogoleva correctionbylaennecofchronicironoverloadliverkidneysandbrain