Apigenin ameliorates imiquimod-induced psoriasis in C57BL/6J mice by inactivating STAT3 and NF-κB

Apigenin ameliorates imiquimod-induced psoriasis in C57BL/6J mice by inactivating STAT3 and NF-κB

Psoriasis is a chronic autoimmune disease featured by patches on the skin. It is caused by malfunction of immune cells and keratinocytes with inflammation as one of its key features. Apigenin (API) is a natural flavonoid with anti-inflammatory and immunoregulatory properties. Therefore, we speculate...

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Bibliographic Details
Main Authors: Xianshe Meng, Shihong Zheng, Zequn Yin, Xuerui Wang, Daigang Yang, Tingfeng Zou, Huaxin Li, Yuanli Chen, Chenzhong Liao, Zhouling Xie, Xiaodong Fan, Jihong Han, Yajun Duan, Xiaoxiao Yang
Format: Article
Language:English
Published: Tsinghua University Press 2024-01-01
Series:Food Science and Human Wellness
Subjects:
Psoriasis
Apigenin
Imiquimod
Inflammation
Signal transducer activator of transcription 3 (STAT3)
Nuclear factor-κB (NF-κB)
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453023001118
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