Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer

The sign of Leser-Trélat is a rare paraneoplastic phenomenon marked by accelerated onset of multiple seborrheic keratoses. The occurrence of the sign often points towards underlying visceral malignancies which in a majority are adenocarcinomas of the gastrointestinal tract. We report this case of a...

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Main Authors: Vinaya Gaduputi, Chaitanya Chandrala, Hassan Tariq, Kalyan Kanneganti
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2014/825929
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author Vinaya Gaduputi
Chaitanya Chandrala
Hassan Tariq
Kalyan Kanneganti
author_facet Vinaya Gaduputi
Chaitanya Chandrala
Hassan Tariq
Kalyan Kanneganti
author_sort Vinaya Gaduputi
collection DOAJ
description The sign of Leser-Trélat is a rare paraneoplastic phenomenon marked by accelerated onset of multiple seborrheic keratoses. The occurrence of the sign often points towards underlying visceral malignancies which in a majority are adenocarcinomas of the gastrointestinal tract. We report this case of a 65-year-old man who presented with sign of Leser-Trélat and was diagnosed with poorly differentiated squamous cell cancer of the esophagus. To our knowledge this is only the second such reported association of Leser-Trélat sign with squamous cell cancer of esophagus.
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series Case Reports in Oncological Medicine
spelling doaj-art-6982894a4e3541d6a41a8fd4fa0a5f2f2025-08-20T02:23:55ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/825929825929Sign of Leser-Trélat Associated with Esophageal Squamous Cell CancerVinaya Gaduputi0Chaitanya Chandrala1Hassan Tariq2Kalyan Kanneganti3Department of Medicine, Bronx Lebanon Hospital Center, 1650 Selwyn Avenue, Suite No. 10C, Bronx, NY 10457, USADepartment of Medicine, Bronx Lebanon Hospital Center, 1650 Selwyn Avenue, Suite No. 10C, Bronx, NY 10457, USADepartment of Medicine, Bronx Lebanon Hospital Center, 1650 Selwyn Avenue, Suite No. 10C, Bronx, NY 10457, USADepartment of Medicine, Bronx Lebanon Hospital Center, 1650 Selwyn Avenue, Suite No. 10C, Bronx, NY 10457, USAThe sign of Leser-Trélat is a rare paraneoplastic phenomenon marked by accelerated onset of multiple seborrheic keratoses. The occurrence of the sign often points towards underlying visceral malignancies which in a majority are adenocarcinomas of the gastrointestinal tract. We report this case of a 65-year-old man who presented with sign of Leser-Trélat and was diagnosed with poorly differentiated squamous cell cancer of the esophagus. To our knowledge this is only the second such reported association of Leser-Trélat sign with squamous cell cancer of esophagus.http://dx.doi.org/10.1155/2014/825929
spellingShingle Vinaya Gaduputi
Chaitanya Chandrala
Hassan Tariq
Kalyan Kanneganti
Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer
Case Reports in Oncological Medicine
title Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer
title_full Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer
title_fullStr Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer
title_full_unstemmed Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer
title_short Sign of Leser-Trélat Associated with Esophageal Squamous Cell Cancer
title_sort sign of leser trelat associated with esophageal squamous cell cancer
url http://dx.doi.org/10.1155/2014/825929
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AT chaitanyachandrala signoflesertrelatassociatedwithesophagealsquamouscellcancer
AT hassantariq signoflesertrelatassociatedwithesophagealsquamouscellcancer
AT kalyankanneganti signoflesertrelatassociatedwithesophagealsquamouscellcancer