POLYMORPHISMS OF EXTRACELLULAR CONNECTIVE TISSUE REMODELING PROTEINASES AND <i>MMP2, MMP3, MMP9</i> GENES, AND NEOANGIGENESIS <i>VEGF</i> GENE IN RETINAL MICROANGIOPATHY IN THE PATIENTS WITH TYPE 2 DIABETES MELLITUS

POLYMORPHISMS OF EXTRACELLULAR CONNECTIVE TISSUE REMODELING PROTEINASES AND <i>MMP2, MMP3, MMP9</i> GENES, AND NEOANGIGENESIS <i>VEGF</i> GENE IN RETINAL MICROANGIOPATHY IN THE PATIENTS WITH TYPE 2 DIABETES MELLITUS

The aim of our study was to perform an association analysis between MMP2, MMP3, MMP9, VEGF gene polymorphisms and development of non-proliferative diabetic retinopathy (DR) in the type 2 diabetic patients (DM).201 DM patients: 90 cases of DR and 111 subjects without DR features were included into th...

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Bibliographic Details
Main Authors: A. V. Shevchenko, V. F. Prokofiev, V. I. Konenkov, V. V. Klimontov, N. V. Tyan, D. V. Chernykh, A. N. Trunov, V. V. Chernykh
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2019-07-01
Series:Медицинская иммунология
Subjects:
diabetic retinopathy
matrix metalloproteinases genes
vascular endothelial growth factor gene
genic networks
mathematical modelling
Online Access:https://www.mimmun.ru/mimmun/article/view/1817
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