Impact of Biologics and Proton Pump Inhibitors on Gastrointestinal Infection Risk in Inflammatory Bowel Disease Patients: A Retrospective Analysis of Pathogen-Specific Outcomes and Treatment Interactions

Impact of Biologics and Proton Pump Inhibitors on Gastrointestinal Infection Risk in Inflammatory Bowel Disease Patients: A Retrospective Analysis of Pathogen-Specific Outcomes and Treatment Interactions

<b>Background/Objectives</b>: Inflammatory bowel disease (IBD) patients face elevated gastrointestinal (GI) infection risks due to immune dysregulation and gut dysbiosis. While steroids and immunosuppressants are known to increase infection risk, data on biologics and proton pump inhibit...

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Bibliographic Details
Main Authors: Ryan Njeim, Elie Moussa, Chapman Wei, Joelle Sleiman, Reem Dimachkie, Liliane Deeb
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
inflammatory bowel disease
biologic therapy
proton pump inhibitors
gastrointestinal infections
clostridioides difficile
Online Access:https://www.mdpi.com/2227-9059/13/7/1676
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