Predictive value of liver enzymes in long-term prognosis of hepatic Wilson disease: results from the Wilson AEEH registry

Predictive value of liver enzymes in long-term prognosis of hepatic Wilson disease: results from the Wilson AEEH registry

Abstract Background and Aims Monitoring Wilson disease (WD) is challenging due to its variable presentation and the absence of reliable biomarkers. This study aims to assess the predictive value of liver enzymes, particularly transaminases, on long-term outcomes in patients with hepatic WD using dat...

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Main Authors: Marina Berenguer, Luis García-Villarreal, Antonio Olveira, Esther Mollina Pérez, José María Moreno Planas, Marta Romero-Gutiérrez, José María Pinazo Bandera, Helena Masnou Ridaura, Paula Iruzubieta, María Luisa González Diéguez, Javier Ampuero, José Ramón Fernández Ramos, Carolina Muñoz, Ana Arencibia Almeida, Sara Lorente, Manuel Delgado Blanco, Diego Burgos Santamaría, Mònica Pons Delgado, Alba Cachero, Manuel Hernández Guerra, Judith Gómez Camarero, Sergio Gil Rojas, María Lázaro Ríos, Isabel Carmona Soria, Gemma Carrión, Ariadna Bono, Anna Miralpeix, Pablo Alonso Castellano, Zoe Mariño, Registro Wilson-AEEH
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Wilson disease
Spanish Wilson registry
Transaminases
Cirrhosis
Fibrosis progression
Online Access:https://doi.org/10.1186/s13023-025-03821-1
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