Stress, epileptiform symptoms in schizophrenia and neural information transmission

Several findings indicate that stress may influence epileptiform discharges manifesting in temporal-limbic areas, which may become a potential trigger of psychosis that may manifest without neurologically diagnosed epilepsy. Some findings suggest that measures assessing levels of inter-hemispheric i...

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Main Authors: Simek Jakub, Bob Petr, Pec Ondrej, Chladek Jan, Hajny Jakub, Raboch Jiri
Format: Article
Language:English
Published: De Gruyter 2025-05-01
Series:Translational Neuroscience
Subjects:
Online Access:https://doi.org/10.1515/tnsci-2025-0372
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author Simek Jakub
Bob Petr
Pec Ondrej
Chladek Jan
Hajny Jakub
Raboch Jiri
author_facet Simek Jakub
Bob Petr
Pec Ondrej
Chladek Jan
Hajny Jakub
Raboch Jiri
author_sort Simek Jakub
collection DOAJ
description Several findings indicate that stress may influence epileptiform discharges manifesting in temporal-limbic areas, which may become a potential trigger of psychosis that may manifest without neurologically diagnosed epilepsy. Some findings suggest that measures assessing levels of inter-hemispheric information connection may reveal the spread of subclinical epileptiform neural activity associated with psychotic and seizure-like symptoms. Recent research also suggests that electrodermal activity (EDA), which is related to limbic activations, may allow indirect measurement of interhemispheric information transmission. These findings about the interhemispheric spread of information suggest a hypothesis that heightened spread of information between the brain hemispheres might indirectly indicate epileptiform discharges spreading between hemispheres.
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series Translational Neuroscience
spelling doaj-art-696b9bcb8b644c7dabff714a05d84e8a2025-08-20T03:07:05ZengDe GruyterTranslational Neuroscience2081-69362025-05-011612759010.1515/tnsci-2025-0372Stress, epileptiform symptoms in schizophrenia and neural information transmissionSimek Jakub0Bob Petr1Pec Ondrej2Chladek Jan3Hajny Jakub4Raboch Jiri5Center for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry & UHSL, 1st Faculty of Medicine, Charles University, Ke Karlovu 11, Prague, 128 00, Czech RepublicCenter for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry & UHSL, 1st Faculty of Medicine, Charles University, Ke Karlovu 11, Prague, 128 00, Czech RepublicCenter for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry & UHSL, 1st Faculty of Medicine, Charles University, Ke Karlovu 11, Prague, 128 00, Czech RepublicCenter for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry & UHSL, 1st Faculty of Medicine, Charles University, Ke Karlovu 11, Prague, 128 00, Czech RepublicCenter for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry & UHSL, 1st Faculty of Medicine, Charles University, Ke Karlovu 11, Prague, 128 00, Czech RepublicCenter for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry & UHSL, 1st Faculty of Medicine, Charles University, Ke Karlovu 11, Prague, 128 00, Czech RepublicSeveral findings indicate that stress may influence epileptiform discharges manifesting in temporal-limbic areas, which may become a potential trigger of psychosis that may manifest without neurologically diagnosed epilepsy. Some findings suggest that measures assessing levels of inter-hemispheric information connection may reveal the spread of subclinical epileptiform neural activity associated with psychotic and seizure-like symptoms. Recent research also suggests that electrodermal activity (EDA), which is related to limbic activations, may allow indirect measurement of interhemispheric information transmission. These findings about the interhemispheric spread of information suggest a hypothesis that heightened spread of information between the brain hemispheres might indirectly indicate epileptiform discharges spreading between hemispheres.https://doi.org/10.1515/tnsci-2025-0372schizophreniaelectrodermal activityepileptiform activitytransinformationtemporal epileptic-like symptomsstress
spellingShingle Simek Jakub
Bob Petr
Pec Ondrej
Chladek Jan
Hajny Jakub
Raboch Jiri
Stress, epileptiform symptoms in schizophrenia and neural information transmission
Translational Neuroscience
schizophrenia
electrodermal activity
epileptiform activity
transinformation
temporal epileptic-like symptoms
stress
title Stress, epileptiform symptoms in schizophrenia and neural information transmission
title_full Stress, epileptiform symptoms in schizophrenia and neural information transmission
title_fullStr Stress, epileptiform symptoms in schizophrenia and neural information transmission
title_full_unstemmed Stress, epileptiform symptoms in schizophrenia and neural information transmission
title_short Stress, epileptiform symptoms in schizophrenia and neural information transmission
title_sort stress epileptiform symptoms in schizophrenia and neural information transmission
topic schizophrenia
electrodermal activity
epileptiform activity
transinformation
temporal epileptic-like symptoms
stress
url https://doi.org/10.1515/tnsci-2025-0372
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