The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal Health
Bacteriocins produced by lactic acid bacteria (LAB) are promising bioactive peptides. Intriguingly, bacteriocins have health benefits to the host and may be applied safely in the food industry as bio-preservatives or as therapeutic interventions preventing intestinal diseases. In recent years, findi...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Foods |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2304-8158/13/23/3887 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850260468715749376 |
|---|---|
| author | Mohamedelfatieh Ismael Mingxin Huang Qingping Zhong |
| author_facet | Mohamedelfatieh Ismael Mingxin Huang Qingping Zhong |
| author_sort | Mohamedelfatieh Ismael |
| collection | DOAJ |
| description | Bacteriocins produced by lactic acid bacteria (LAB) are promising bioactive peptides. Intriguingly, bacteriocins have health benefits to the host and may be applied safely in the food industry as bio-preservatives or as therapeutic interventions preventing intestinal diseases. In recent years, finding a safe alternative approach to conventional treatments to promote gut health is a scientific hotspot. Therefore, this review aimed to give insight into the promising applications of LAB-bacteriocins in preventing intestinal diseases, such as colonic cancer, <i>Helicobacter pylori</i> infections, multidrug-resistant infection-associated colitis, viral gastroenteritis, inflammatory bowel disease, and obesity disorders. Moreover, we highlighted the recent research on bacteriocins promoting gastrointestinal health. The review also provided insights into the proposed mechanisms, challenges and opportunities, trends and prospects. In addition, a SWOT analysis was conducted on the potential applications. Based on properties, biosafety, and health functions of LAB-bacteriocins, we conclude that the future applications of LAB-bacteriocins are promising in promoting gastrointestinal health. Further in vivo trials are needed to confirm these potential effects of LAB-bacteriocins interventions. |
| format | Article |
| id | doaj-art-6969730b8b3c44f8bc84b1c4c42dec3a |
| institution | OA Journals |
| issn | 2304-8158 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj-art-6969730b8b3c44f8bc84b1c4c42dec3a2025-08-20T01:55:38ZengMDPI AGFoods2304-81582024-12-011323388710.3390/foods13233887The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal HealthMohamedelfatieh Ismael0Mingxin Huang1Qingping Zhong2Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, ChinaBacteriocins produced by lactic acid bacteria (LAB) are promising bioactive peptides. Intriguingly, bacteriocins have health benefits to the host and may be applied safely in the food industry as bio-preservatives or as therapeutic interventions preventing intestinal diseases. In recent years, finding a safe alternative approach to conventional treatments to promote gut health is a scientific hotspot. Therefore, this review aimed to give insight into the promising applications of LAB-bacteriocins in preventing intestinal diseases, such as colonic cancer, <i>Helicobacter pylori</i> infections, multidrug-resistant infection-associated colitis, viral gastroenteritis, inflammatory bowel disease, and obesity disorders. Moreover, we highlighted the recent research on bacteriocins promoting gastrointestinal health. The review also provided insights into the proposed mechanisms, challenges and opportunities, trends and prospects. In addition, a SWOT analysis was conducted on the potential applications. Based on properties, biosafety, and health functions of LAB-bacteriocins, we conclude that the future applications of LAB-bacteriocins are promising in promoting gastrointestinal health. Further in vivo trials are needed to confirm these potential effects of LAB-bacteriocins interventions.https://www.mdpi.com/2304-8158/13/23/3887lactic acid bacteriabacteriocinsgastrointestinal healthapplication |
| spellingShingle | Mohamedelfatieh Ismael Mingxin Huang Qingping Zhong The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal Health Foods lactic acid bacteria bacteriocins gastrointestinal health application |
| title | The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal Health |
| title_full | The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal Health |
| title_fullStr | The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal Health |
| title_full_unstemmed | The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal Health |
| title_short | The Bacteriocins Produced by Lactic Acid Bacteria and the Promising Applications in Promoting Gastrointestinal Health |
| title_sort | bacteriocins produced by lactic acid bacteria and the promising applications in promoting gastrointestinal health |
| topic | lactic acid bacteria bacteriocins gastrointestinal health application |
| url | https://www.mdpi.com/2304-8158/13/23/3887 |
| work_keys_str_mv | AT mohamedelfatiehismael thebacteriocinsproducedbylacticacidbacteriaandthepromisingapplicationsinpromotinggastrointestinalhealth AT mingxinhuang thebacteriocinsproducedbylacticacidbacteriaandthepromisingapplicationsinpromotinggastrointestinalhealth AT qingpingzhong thebacteriocinsproducedbylacticacidbacteriaandthepromisingapplicationsinpromotinggastrointestinalhealth AT mohamedelfatiehismael bacteriocinsproducedbylacticacidbacteriaandthepromisingapplicationsinpromotinggastrointestinalhealth AT mingxinhuang bacteriocinsproducedbylacticacidbacteriaandthepromisingapplicationsinpromotinggastrointestinalhealth AT qingpingzhong bacteriocinsproducedbylacticacidbacteriaandthepromisingapplicationsinpromotinggastrointestinalhealth |