Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature Review
Introduction: Polycythemia is a rare condition that can be either primary or secondary. We report a case of an adolescent with progressive hydronephrosis-induced polycythemia and low erythropoietin levels, along with a thorough literature review. Report of a Case: A 17-year-old girl with epilepsy ha...
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2024-12-01
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| author | Chia-Cheng Chang Jiann-Shiuh Chen Chao-Ching Huang Yuan-Ning Yang Chih-Chia Chen |
| author_facet | Chia-Cheng Chang Jiann-Shiuh Chen Chao-Ching Huang Yuan-Ning Yang Chih-Chia Chen |
| author_sort | Chia-Cheng Chang |
| collection | DOAJ |
| description | Introduction: Polycythemia is a rare condition that can be either primary or secondary. We report a case of an adolescent with progressive hydronephrosis-induced polycythemia and low erythropoietin levels, along with a thorough literature review. Report of a Case: A 17-year-old girl with epilepsy had progressively elevated hemoglobin levels and low erythropoietin levels. Initial investigations, including genetic surveys and bone marrow studies, showed no evidence of polycythemia vera or myeloproliferative disorders. Further imaging studies revealed severe hydronephrosis on the left side caused by ureteropelvic junction stenosis. Following nephroureterectomy, her hemoglobin levels gradually returned to normal. Conclusions: This case highlights the potential association between hydronephrosis and polycythemia, even with low erythropoietin levels. Renal abnormalities should be considered in the differential diagnosis of pediatric patients with polycythemia, even in the absence of elevation of erythropoietin. Further research is needed to clarify this association and its pathophysiology. |
| format | Article |
| id | doaj-art-6968380cd53648e5a7e6de2b6cee5a34 |
| institution | OA Journals |
| issn | 2227-9067 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj-art-6968380cd53648e5a7e6de2b6cee5a342025-08-20T02:00:19ZengMDPI AGChildren2227-90672024-12-011112153410.3390/children11121534Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature ReviewChia-Cheng Chang0Jiann-Shiuh Chen1Chao-Ching Huang2Yuan-Ning Yang3Chih-Chia Chen4Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704302, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704302, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704302, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704302, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704302, TaiwanIntroduction: Polycythemia is a rare condition that can be either primary or secondary. We report a case of an adolescent with progressive hydronephrosis-induced polycythemia and low erythropoietin levels, along with a thorough literature review. Report of a Case: A 17-year-old girl with epilepsy had progressively elevated hemoglobin levels and low erythropoietin levels. Initial investigations, including genetic surveys and bone marrow studies, showed no evidence of polycythemia vera or myeloproliferative disorders. Further imaging studies revealed severe hydronephrosis on the left side caused by ureteropelvic junction stenosis. Following nephroureterectomy, her hemoglobin levels gradually returned to normal. Conclusions: This case highlights the potential association between hydronephrosis and polycythemia, even with low erythropoietin levels. Renal abnormalities should be considered in the differential diagnosis of pediatric patients with polycythemia, even in the absence of elevation of erythropoietin. Further research is needed to clarify this association and its pathophysiology.https://www.mdpi.com/2227-9067/11/12/1534polycythemiahydronephrosiserythropoietin |
| spellingShingle | Chia-Cheng Chang Jiann-Shiuh Chen Chao-Ching Huang Yuan-Ning Yang Chih-Chia Chen Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature Review Children polycythemia hydronephrosis erythropoietin |
| title | Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature Review |
| title_full | Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature Review |
| title_fullStr | Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature Review |
| title_full_unstemmed | Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature Review |
| title_short | Hydronephrosis-Induced Polycythemia with Low Erythropoietin Level: A Case Report and Literature Review |
| title_sort | hydronephrosis induced polycythemia with low erythropoietin level a case report and literature review |
| topic | polycythemia hydronephrosis erythropoietin |
| url | https://www.mdpi.com/2227-9067/11/12/1534 |
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