Enhanced immunotherapy response in lung adenocarcinoma patients with COPD: insights into tumor cells and immune microenvironment characteristics

Enhanced immunotherapy response in lung adenocarcinoma patients with COPD: insights into tumor cells and immune microenvironment characteristics

Abstract Background Lung cancer and chronic obstructive pulmonary disease (COPD) are major global health challenges, and their coexistence in patients presents unique clinical complexities. Interestingly, patients with both lung adenocarcinoma (LUAD) and COPD show reduced responses to conventional c...

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Bibliographic Details
Main Authors: Yuji Huang, Boxuan Liang, Xuewei Chen, Zhiming Li, Yanhong Deng, Jiaxin Du, Yizhou Zhong, Xi Lin, Junjun Fu, Jieyu Xie, Xin Zhang, Zhenlie Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell Communication and Signaling
Subjects:
Lung cancer
Obstructive lung disease
Malignant cells
Tumor immune microenvironment
Human leukocyte antigen I
C-X-C motif chemokine ligand 13
Online Access:https://doi.org/10.1186/s12964-025-02332-7
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