High genetic variability of Schmallenberg virus M-segment leads to efficient immune escape from neutralizing antibodies.

High genetic variability of Schmallenberg virus M-segment leads to efficient immune escape from neutralizing antibodies.

Schmallenberg virus (SBV) is the cause of severe fetal malformations when immunologically naïve pregnant ruminants are infected. In those malformed fetuses, a "hot-spot"-region of high genetic variability within the N-terminal region of the viral envelope protein Gc has been observed previ...

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Bibliographic Details
Main Authors: Kerstin Wernike, Ilona Reimann, Ashley C Banyard, Franziska Kraatz, S Anna La Rocca, Bernd Hoffmann, Sarah McGowan, Silke Hechinger, Bhudipa Choudhury, Andrea Aebischer, Falko Steinbach, Martin Beer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009247&type=printable
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