High genetic variability of Schmallenberg virus M-segment leads to efficient immune escape from neutralizing antibodies.
Schmallenberg virus (SBV) is the cause of severe fetal malformations when immunologically naïve pregnant ruminants are infected. In those malformed fetuses, a "hot-spot"-region of high genetic variability within the N-terminal region of the viral envelope protein Gc has been observed previ...
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| Main Authors: | Kerstin Wernike, Ilona Reimann, Ashley C Banyard, Franziska Kraatz, S Anna La Rocca, Bernd Hoffmann, Sarah McGowan, Silke Hechinger, Bhudipa Choudhury, Andrea Aebischer, Falko Steinbach, Martin Beer |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009247&type=printable |
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