Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in Poland

St. John’s wort (<i>Hypericum perforatum</i> L.) is a well-known medicinal plant widely used in phytotherapy due to its abundant secondary metabolites with bioactive properties. Research on tocochromanols conducted in nine populations of St. John’s wort using reverse-phase high performan...

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Main Authors: Paweł Górnaś, Edyta Symoniuk
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/5/1137
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author Paweł Górnaś
Edyta Symoniuk
author_facet Paweł Górnaś
Edyta Symoniuk
author_sort Paweł Górnaś
collection DOAJ
description St. John’s wort (<i>Hypericum perforatum</i> L.) is a well-known medicinal plant widely used in phytotherapy due to its abundant secondary metabolites with bioactive properties. Research on tocochromanols conducted in nine populations of St. John’s wort using reverse-phase high performance liquid chromatography with fluorescent light detector (RP-HPLC-FLD) has provided new insights into their diverse composition in different aerial parts of the plant. Flower buds displayed the most diverse tocochromanol profile, while stems contained the lowest levels of these compounds. In most of the examined tissues, δ-T3 was the predominant tocochromanol (34–69%), except in leaves, where α-T dominated. The highest concentration of total tocotrienols was recorded in flower buds (48.5–74.1 mg/100 g dry weight), with δ-T3 (56%) and α-T3 (38%) as the dominant compounds. The highest δ-T3 content was found in unripe seed pods (29.6–45.1 mg/100 g dw). Principal Component Analysis (PCA) revealed distinct differences in tocochromanol composition among the aerial parts of <i>H. perforatum</i>. The findings highlight that <i>H. perforatum</i> has higher potential applications in the food, pharmaceutical, and medical industries than previously assumed, due to its relatively high content of tocotrienols, mainly δ-T3, in different plant organs.
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spelling doaj-art-691aaacf7ff14e819cf9d1c27eba835d2025-08-20T02:59:15ZengMDPI AGMolecules1420-30492025-03-01305113710.3390/molecules30051137Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in PolandPaweł Górnaś0Edyta Symoniuk1Institute of Horticulture, Graudu 1, LV-3701 Dobele, LatviaDepartment of Food Technology and Assessment, Institute of Food Sciences, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, PolandSt. John’s wort (<i>Hypericum perforatum</i> L.) is a well-known medicinal plant widely used in phytotherapy due to its abundant secondary metabolites with bioactive properties. Research on tocochromanols conducted in nine populations of St. John’s wort using reverse-phase high performance liquid chromatography with fluorescent light detector (RP-HPLC-FLD) has provided new insights into their diverse composition in different aerial parts of the plant. Flower buds displayed the most diverse tocochromanol profile, while stems contained the lowest levels of these compounds. In most of the examined tissues, δ-T3 was the predominant tocochromanol (34–69%), except in leaves, where α-T dominated. The highest concentration of total tocotrienols was recorded in flower buds (48.5–74.1 mg/100 g dry weight), with δ-T3 (56%) and α-T3 (38%) as the dominant compounds. The highest δ-T3 content was found in unripe seed pods (29.6–45.1 mg/100 g dw). Principal Component Analysis (PCA) revealed distinct differences in tocochromanol composition among the aerial parts of <i>H. perforatum</i>. The findings highlight that <i>H. perforatum</i> has higher potential applications in the food, pharmaceutical, and medical industries than previously assumed, due to its relatively high content of tocotrienols, mainly δ-T3, in different plant organs.https://www.mdpi.com/1420-3049/30/5/1137<i>Guttiferaceae</i><i>Hypericaceae</i>herbphytomedicinebioactive lipophilic phytochemicalstocol
spellingShingle Paweł Górnaś
Edyta Symoniuk
Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in Poland
Molecules
<i>Guttiferaceae</i>
<i>Hypericaceae</i>
herb
phytomedicine
bioactive lipophilic phytochemicals
tocol
title Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in Poland
title_full Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in Poland
title_fullStr Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in Poland
title_full_unstemmed Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in Poland
title_short Tocotrienols in Different Parts of Wild <i>Hypericum perforatum</i> L. Populations in Poland
title_sort tocotrienols in different parts of wild i hypericum perforatum i l populations in poland
topic <i>Guttiferaceae</i>
<i>Hypericaceae</i>
herb
phytomedicine
bioactive lipophilic phytochemicals
tocol
url https://www.mdpi.com/1420-3049/30/5/1137
work_keys_str_mv AT pawełgornas tocotrienolsindifferentpartsofwildihypericumperforatumilpopulationsinpoland
AT edytasymoniuk tocotrienolsindifferentpartsofwildihypericumperforatumilpopulationsinpoland