Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt
Abstract Background The COVID-19 global pandemic significantly impacted populations of all ages. While initially thought to affect adults predominantly, it became clear that children and adolescents were also susceptible to the virus's effects. This study aims to explore the epidemiological pat...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-02-01
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| Series: | Egyptian Pediatric Association Gazette |
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| Online Access: | https://doi.org/10.1186/s43054-024-00341-8 |
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| author | Salma ZEl Houchi Hanaa I. Rady Iman Iskander Tamer Abdel Hamid Salma Abdelrehim Seddik Amira Aly Hegazy Ahmed Taha Aboushady Mohamed Eissa Sherine Khamis Hussein Dina Hanoura Miriam Magdy Aziz Remon Magdy Heba Ahmed ElAwady Esraa A. Elmazzahy |
| author_facet | Salma ZEl Houchi Hanaa I. Rady Iman Iskander Tamer Abdel Hamid Salma Abdelrehim Seddik Amira Aly Hegazy Ahmed Taha Aboushady Mohamed Eissa Sherine Khamis Hussein Dina Hanoura Miriam Magdy Aziz Remon Magdy Heba Ahmed ElAwady Esraa A. Elmazzahy |
| author_sort | Salma ZEl Houchi |
| collection | DOAJ |
| description | Abstract Background The COVID-19 global pandemic significantly impacted populations of all ages. While initially thought to affect adults predominantly, it became clear that children and adolescents were also susceptible to the virus's effects. This study aims to explore the epidemiological patterns, clinical features, laboratory and radiological characteristics, and outcomes of COVID-19 infection in a group of Egyptian children (≤ 18 years). Methods This observational, cross-sectional study is based on a multicenter questionnaire sent to pediatricians managing COVID-19-infected children, through a convenient sampling approach. The clinical picture and investigations of 253 pediatric cases were included. Results Most cases (42%) occurred in children aged 3–10 years, and a slightly higher incidence in males. Eighty-two percent of the cases presented with fever; most patients had lymphopenia and elevated CRP, 59% and 74%, respectively. The most common CT chest finding (done for 85 patients) was a bilateral ground glass appearance, which appeared in almost 45% of the patients. The disease severity was higher in infants < 1 year. Severe and critical forms of the disease were significantly associated with high ferritin and d-dimer. The severity of the disease varied, with infants under one year of age having the highest percentage of severe and critical cases, with a 15% the mortality rate, when compared to other age groups. Conclusion COVID-19 has a wide clinical spectrum of diseases ranging from asymptomatic to severe and critical. In severe and critical cases, death was more common among those with elevated ferritin and d-dimer levels. Infants are more vulnerable to severe forms of the disease. |
| format | Article |
| id | doaj-art-69188cec945c4882a503daf1aa37810c |
| institution | Kabale University |
| issn | 2090-9942 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Egyptian Pediatric Association Gazette |
| spelling | doaj-art-69188cec945c4882a503daf1aa37810c2025-02-09T12:24:57ZengSpringerOpenEgyptian Pediatric Association Gazette2090-99422025-02-0173111210.1186/s43054-024-00341-8Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in EgyptSalma ZEl Houchi0Hanaa I. Rady1Iman Iskander2Tamer Abdel Hamid3Salma Abdelrehim Seddik4Amira Aly Hegazy5Ahmed Taha Aboushady6Mohamed Eissa7Sherine Khamis Hussein8Dina Hanoura9Miriam Magdy Aziz10Remon Magdy11Heba Ahmed ElAwady12Esraa A. Elmazzahy13Pediatrics Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityPediatrics Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityPediatrics Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityPediatrics Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityPublic Health and Community Medicine Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityPublic Health and Community Medicine Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityFaculty of Medicine, Alexandria UniversityFaculty of Medicine, Alexandria UniversityPediatrics Department, Fayoum UniversityPediatrician, Ministry of Health and PopulationPediatrics Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityPediatrics Department, Fayoum UniversityPediatrics Department, Fayoum UniversityPediatrics Department, Kasr Al Ainy Faculty of Medicine, Cairo UniversityAbstract Background The COVID-19 global pandemic significantly impacted populations of all ages. While initially thought to affect adults predominantly, it became clear that children and adolescents were also susceptible to the virus's effects. This study aims to explore the epidemiological patterns, clinical features, laboratory and radiological characteristics, and outcomes of COVID-19 infection in a group of Egyptian children (≤ 18 years). Methods This observational, cross-sectional study is based on a multicenter questionnaire sent to pediatricians managing COVID-19-infected children, through a convenient sampling approach. The clinical picture and investigations of 253 pediatric cases were included. Results Most cases (42%) occurred in children aged 3–10 years, and a slightly higher incidence in males. Eighty-two percent of the cases presented with fever; most patients had lymphopenia and elevated CRP, 59% and 74%, respectively. The most common CT chest finding (done for 85 patients) was a bilateral ground glass appearance, which appeared in almost 45% of the patients. The disease severity was higher in infants < 1 year. Severe and critical forms of the disease were significantly associated with high ferritin and d-dimer. The severity of the disease varied, with infants under one year of age having the highest percentage of severe and critical cases, with a 15% the mortality rate, when compared to other age groups. Conclusion COVID-19 has a wide clinical spectrum of diseases ranging from asymptomatic to severe and critical. In severe and critical cases, death was more common among those with elevated ferritin and d-dimer levels. Infants are more vulnerable to severe forms of the disease.https://doi.org/10.1186/s43054-024-00341-8COVID-19PediatricsAdolescentsInfectious diseasesEpidemiology |
| spellingShingle | Salma ZEl Houchi Hanaa I. Rady Iman Iskander Tamer Abdel Hamid Salma Abdelrehim Seddik Amira Aly Hegazy Ahmed Taha Aboushady Mohamed Eissa Sherine Khamis Hussein Dina Hanoura Miriam Magdy Aziz Remon Magdy Heba Ahmed ElAwady Esraa A. Elmazzahy Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt Egyptian Pediatric Association Gazette COVID-19 Pediatrics Adolescents Infectious diseases Epidemiology |
| title | Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt |
| title_full | Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt |
| title_fullStr | Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt |
| title_full_unstemmed | Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt |
| title_short | Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt |
| title_sort | profile of egyptian pediatrics with covid 19 insights from healthcare providers in egypt |
| topic | COVID-19 Pediatrics Adolescents Infectious diseases Epidemiology |
| url | https://doi.org/10.1186/s43054-024-00341-8 |
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