Protective Effect of Lycopene on Ifosfamide-Induced Mitophagy through Pink, Parkin, and LC3-I/II Pathway in Testicular Tissue

Protective Effect of Lycopene on Ifosfamide-Induced Mitophagy through Pink, Parkin, and LC3-I/II Pathway in Testicular Tissue

Background: Ifosfamide (IFO) is a widely used chemotherapeutic agent that exerts cytotoxic effects through various mechanisms, including the induction of apoptosis and oxidative stress. However, its use is associated with detrimen­tal effects on male reproductive health, including mitochondrial dysf...

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Bibliographic Details
Main Authors: Ali Thoulfikar A. Imeer, Moona Roshanfekr Rad, Sara Abedi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2025-07-01
Series:International Journal of Fertility and Sterility
Subjects:
ifosfamide
lycopene
mitophagy
testicles
Online Access:https://www.ijfs.ir/article_719395_ab46104ee803a82348d6649011d21470.pdf
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