HDAC9-Mediated Pyroptosis Promotes Orthodontically Induced Inflammatory Root Resorption

HDAC9-Mediated Pyroptosis Promotes Orthodontically Induced Inflammatory Root Resorption

Introduction and aims: Orthodontically induced inflammatory root resorption (OIIRR) is a common iatrogenic outcome of orthodontic treatment. Both epigenetic modifications and pyroptosis have demonstrated a certain role in OIIRR. This study aims to investigate whether epigenetic modifications regulat...

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Bibliographic Details
Main Authors: Lin Chen, Limin Liu, Tianwei Lin, Zhihui Mai, Hongfei Lu, Bingxue Hu, Junhao Huang, Hong Ai
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:International Dental Journal
Subjects:
HDAC9
Pyroptosis
Periodontal ligament fibroblasts
Orthodontically induced inflammatory root resorption
Mitochondrial dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S002065392500098X
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