Nymphaea pubescens Willd. extract and its flavonoid constituents vasodilate rat isolated pulmonary artery via NO-sGC-cGMP pathway
Background: Pulmonary arterial hypertension (PAH) is a progressive disorder indicated by elevated blood pressure in pulmonary artery (PA). PAH treatment focuses on inducing PA vasodilation by inhibiting phosphodiesterase 5 (PDE5), the enzyme prominently expressed in pulmonary vasculature. Our previo...
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Main Authors: | Teerapap Panklai, Prapapan Temkitthawon, Nungruthai Suphrom, Corine Girard, Perle Totoson, Kowit Hengphasatporn, Yasuteru Shigeta, Krongkarn Chootip, Kornkanok Ingkaninan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Phytomedicine Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667031325000065 |
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