Autoprobiotic therapy
The results are presented of the experimental study of survival rates of autologous bifidobacteria and lactobacilli strains (autostrains) in the intestines of conventional white mice and guinea pigs, as well as an assessment of the effectiveness of the use of isolated bifidobacteria and lactobacilli...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/200 |
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| author | I. Yu. Chicherin I. P. Pogorelsky I. A. Lundovskikh K. E. Gavrilov M. R. Shabalina I. V. Darmov |
| author_facet | I. Yu. Chicherin I. P. Pogorelsky I. A. Lundovskikh K. E. Gavrilov M. R. Shabalina I. V. Darmov |
| author_sort | I. Yu. Chicherin |
| collection | DOAJ |
| description | The results are presented of the experimental study of survival rates of autologous bifidobacteria and lactobacilli strains (autostrains) in the intestines of conventional white mice and guinea pigs, as well as an assessment of the effectiveness of the use of isolated bifidobacteria and lactobacilli autostrains in the correction of microecological disorders in the intestines of animals with antibiotic-associated dysbacteriosis. Bifidobacteria and lactobacilli autostrains isolated from intestinal contents of conventional white mice and guinea pigs, as well as rifampicin-resistant derivatives of isolated bacterial autostrains were used in the experiments. It is found that rifampicin-resistant derivatives of bifidobacteria and lactobacilli autostrains retain species and genetically fixed sign of antibiotic resistance. Administered orally to experimental animals, autostrains of bifidobacteria and lactobacilli do not survive in the intestines of animals and are eliminated to 4 days after cessation of administration. Bifidobacteria and lactobacilli autostrains exert virtually no influence on the recovery of the intestinal microbiota in experimental animals with antibiotic-associated dysbacteriosis unlike lactobacilli metabolites and prebiotic Stimbifid, efficiently restoring intestinal microbiota in a short time |
| format | Article |
| id | doaj-art-68e0ce5418bb45ac9a67889e3ba89224 |
| institution | DOAJ |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2014-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-68e0ce5418bb45ac9a67889e3ba892242025-08-20T02:55:16ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0154435410.22625/2072-6732-2013-5-4-43-54214Autoprobiotic therapyI. Yu. Chicherin0I. P. Pogorelsky1I. A. Lundovskikh2K. E. Gavrilov3M. R. Shabalina4I. V. Darmov5Scientific Society «Microbiota», Sergiev PosadVyatka State University, KirovVyatka State University, KirovVyatka State University, KirovVyatka State University, KirovVyatka State University, KirovThe results are presented of the experimental study of survival rates of autologous bifidobacteria and lactobacilli strains (autostrains) in the intestines of conventional white mice and guinea pigs, as well as an assessment of the effectiveness of the use of isolated bifidobacteria and lactobacilli autostrains in the correction of microecological disorders in the intestines of animals with antibiotic-associated dysbacteriosis. Bifidobacteria and lactobacilli autostrains isolated from intestinal contents of conventional white mice and guinea pigs, as well as rifampicin-resistant derivatives of isolated bacterial autostrains were used in the experiments. It is found that rifampicin-resistant derivatives of bifidobacteria and lactobacilli autostrains retain species and genetically fixed sign of antibiotic resistance. Administered orally to experimental animals, autostrains of bifidobacteria and lactobacilli do not survive in the intestines of animals and are eliminated to 4 days after cessation of administration. Bifidobacteria and lactobacilli autostrains exert virtually no influence on the recovery of the intestinal microbiota in experimental animals with antibiotic-associated dysbacteriosis unlike lactobacilli metabolites and prebiotic Stimbifid, efficiently restoring intestinal microbiota in a short timehttps://journal.niidi.ru/jofin/article/view/200probioticprebioticmetabioticmicrobiotadysbacteriosisautostrainswhite miceguinea pigsautoprobiotic therapy |
| spellingShingle | I. Yu. Chicherin I. P. Pogorelsky I. A. Lundovskikh K. E. Gavrilov M. R. Shabalina I. V. Darmov Autoprobiotic therapy Журнал инфектологии probiotic prebiotic metabiotic microbiota dysbacteriosis autostrains white mice guinea pigs autoprobiotic therapy |
| title | Autoprobiotic therapy |
| title_full | Autoprobiotic therapy |
| title_fullStr | Autoprobiotic therapy |
| title_full_unstemmed | Autoprobiotic therapy |
| title_short | Autoprobiotic therapy |
| title_sort | autoprobiotic therapy |
| topic | probiotic prebiotic metabiotic microbiota dysbacteriosis autostrains white mice guinea pigs autoprobiotic therapy |
| url | https://journal.niidi.ru/jofin/article/view/200 |
| work_keys_str_mv | AT iyuchicherin autoprobiotictherapy AT ippogorelsky autoprobiotictherapy AT ialundovskikh autoprobiotictherapy AT kegavrilov autoprobiotictherapy AT mrshabalina autoprobiotictherapy AT ivdarmov autoprobiotictherapy |