Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis

Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis

Chondrocyte is considered the only cell type in cartilage. However, the cell heterogeneity of chondrocytes in human articular cartilage is still not well defined, which hinders our understanding of the pathogenesis of osteoarthritis (OA). Here, we constructed a single-cell transcriptomic atlas of ch...

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Bibliographic Details
Main Authors: Changyuan Huang, Bin Zeng, Bo Zhou, Guanming Chen, Qi Zhang, Wenhong Hou, Guozhi Xiao, Li Duan, Ni Hong, Wenfei Jin
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Genes and Diseases
Subjects:
Cell heterogeneity
Chondrocyte apoptosis
Chondrocyte differentiation
Chondrocyte fibrosis
Osteoarthritis
Single-cell RNA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224000382
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