Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibody
Hemolytic disease of foetus and newborn (HDFN) is a disease characterized by the destruction of fetal red cells by the maternal antibodies which occurs due to allo immunization in the mother by feto-maternal blood group incompatibility.The antibodies most frequently implicated in HDFN may vary depen...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Asian Journal of Transfusion Science |
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| Online Access: | https://journals.lww.com/10.4103/ajts.ajts_154_22 |
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| author | Suresh Kumar Iyyapan Hari Haran Annadurai Gokhula Prasath Thangavel Hemamalini Natesan |
| author_facet | Suresh Kumar Iyyapan Hari Haran Annadurai Gokhula Prasath Thangavel Hemamalini Natesan |
| author_sort | Suresh Kumar Iyyapan |
| collection | DOAJ |
| description | Hemolytic disease of foetus and newborn (HDFN) is a disease characterized by the destruction of fetal red cells by the maternal antibodies which occurs due to allo immunization in the mother by feto-maternal blood group incompatibility.The antibodies most frequently implicated in HDFN may vary depending on the demographic location under consideration. In areas where RhIg administration is available, ABO antibodies are more commonly implicated. Following ABO antibodies, anti-RhD antibodies which are of IgG type are more commonly implicated in causing HDFN. HDFN caused by other Rh system antibodies namely anti-C, anti-c, anti-E, anti- e, MNS, KEL, FY, JK, and DI systems is less frequent. We have reported one such rare case of Hemolytic disease of fetus and newborn due to Anti--S. During the routine antenatal screening for irregular antibodies, using antibody identification cell panel BIO-RAD (ID Diapanel 11x4) which belongs to lot number (06171.47.x – 06271.47.x), anti-S was identified in the mother serum. The baby was non-hydropic at birth with an increase in bilirubin which required high-intensity phototherapy. |
| format | Article |
| id | doaj-art-68d5c13458154457bfed6a344b12fbf0 |
| institution | Kabale University |
| issn | 0973-6247 1998-3565 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Transfusion Science |
| spelling | doaj-art-68d5c13458154457bfed6a344b12fbf02025-01-08T09:10:56ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-12-0118233333510.4103/ajts.ajts_154_22Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibodySuresh Kumar IyyapanHari Haran AnnaduraiGokhula Prasath ThangavelHemamalini NatesanHemolytic disease of foetus and newborn (HDFN) is a disease characterized by the destruction of fetal red cells by the maternal antibodies which occurs due to allo immunization in the mother by feto-maternal blood group incompatibility.The antibodies most frequently implicated in HDFN may vary depending on the demographic location under consideration. In areas where RhIg administration is available, ABO antibodies are more commonly implicated. Following ABO antibodies, anti-RhD antibodies which are of IgG type are more commonly implicated in causing HDFN. HDFN caused by other Rh system antibodies namely anti-C, anti-c, anti-E, anti- e, MNS, KEL, FY, JK, and DI systems is less frequent. We have reported one such rare case of Hemolytic disease of fetus and newborn due to Anti--S. During the routine antenatal screening for irregular antibodies, using antibody identification cell panel BIO-RAD (ID Diapanel 11x4) which belongs to lot number (06171.47.x – 06271.47.x), anti-S was identified in the mother serum. The baby was non-hydropic at birth with an increase in bilirubin which required high-intensity phototherapy.https://journals.lww.com/10.4103/ajts.ajts_154_22alloimmunizationantenatalantibody identificationanti-shemolytic disease of fetus and newborn |
| spellingShingle | Suresh Kumar Iyyapan Hari Haran Annadurai Gokhula Prasath Thangavel Hemamalini Natesan Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibody Asian Journal of Transfusion Science alloimmunization antenatal antibody identification anti-s hemolytic disease of fetus and newborn |
| title | Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibody |
| title_full | Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibody |
| title_fullStr | Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibody |
| title_full_unstemmed | Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibody |
| title_short | Hemolytic disease of fetus and newborn due to maternal AlloAnti-S antibody |
| title_sort | hemolytic disease of fetus and newborn due to maternal alloanti s antibody |
| topic | alloimmunization antenatal antibody identification anti-s hemolytic disease of fetus and newborn |
| url | https://journals.lww.com/10.4103/ajts.ajts_154_22 |
| work_keys_str_mv | AT sureshkumariyyapan hemolyticdiseaseoffetusandnewbornduetomaternalalloantisantibody AT hariharanannadurai hemolyticdiseaseoffetusandnewbornduetomaternalalloantisantibody AT gokhulaprasaththangavel hemolyticdiseaseoffetusandnewbornduetomaternalalloantisantibody AT hemamalininatesan hemolyticdiseaseoffetusandnewbornduetomaternalalloantisantibody |