T cell induced expression of Coronin-1A facilitates blood-brain barrier transmigration of breast cancer cells

Abstract In previous work we discovered that T lymphocytes play a prominent role in the rise of brain metastases of ER-negative breast cancers. In the present study we explored how T lymphocytes promote breast cancer cell penetration through the blood brain barrier (BBB). An in vitro BBB model was e...

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Bibliographic Details
Main Authors: Johan M. Kros, Lona Zeneyedpour, Rute M. S. M. Pedrosa, Zineb Belcaid, Willem A. Dik, Theo M. Luider, Dana A. M. Mustafa
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-83301-x
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