Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation
ObjectiveTo observe the effect of onset of metabolic syndrome （MS） on allograft function after living donor’s kidney transplantation.MethodsFrom August 1，2012 to August 1，2014，clinical data were retrospectively analyzed for 120 recipients of living related renal transplantation. Statistical analysis...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2022-01-01
|
| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.01.006 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849312358668697600 |
|---|---|
| author | Gu Dong-feng Ding Ya-nan Shen Bei-li Zhao He Liu Rui-yong Qu Qing-shan |
| author_facet | Gu Dong-feng Ding Ya-nan Shen Bei-li Zhao He Liu Rui-yong Qu Qing-shan |
| author_sort | Gu Dong-feng |
| collection | DOAJ |
| description | ObjectiveTo observe the effect of onset of metabolic syndrome （MS） on allograft function after living donor’s kidney transplantation.MethodsFrom August 1，2012 to August 1，2014，clinical data were retrospectively analyzed for 120 recipients of living related renal transplantation. Statistical analysis of serum creatine in MS and non-MS groups was conducted by SPSS 16.0 software at Month 3/6，Year 1/3/5 post-transplantation. And t-test was utilized for comparing two groups. Logistic regression was applied for risk factor analysis of MS and <italic>P</italic><0.05 was deemed as significant.ResultsNo significant inter-group difference existed in serum creatine at Month 3 post-transplantation. The mean value and standard deviation were （110.5±27.4） and （109.1±34.0） respectively （<italic>P</italic>>0.05）. At Month 6 post-transplantation，the mean value and standard deviation were （119.2±32.7） and （107.4±24.9） respectively （<italic>P</italic>>0.05）. Significant inter-group difference existed in serum creatine at Year 1 post-transplantation. The mean value and standard deviation were （133.6±39.6） and （106.2±19.2） respectively （<italic>P</italic><0.05）. At Year 3 post-transplantation，the mean value and standard deviation were （230.8±221.6） and （110.6±23.8） respectively （<italic>P</italic><0.01）. At Year 5 post-transplantation，the mean value and standard deviation were （266.2±103.1） and （113.6±26.4） respectively （<italic>P</italic><0.01）. Logistic regression revealed that the risk factors of MS were hyperuricemia，high triglyceride and low high density lipoprotein cholesterol.ConclusionMS is an important health problem in the recipients of kidney transplantation. It is imperative to develop targeted health education and intensify health management. |
| format | Article |
| id | doaj-art-68c5bbcf747f4ed9a39068c543916efc |
| institution | Kabale University |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2022-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-68c5bbcf747f4ed9a39068c543916efc2025-08-20T03:53:07ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902022-01-0122283323110623Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantationGu Dong-fengDing Ya-nanShen Bei-liZhao HeLiu Rui-yongQu Qing-shanObjectiveTo observe the effect of onset of metabolic syndrome （MS） on allograft function after living donor’s kidney transplantation.MethodsFrom August 1，2012 to August 1，2014，clinical data were retrospectively analyzed for 120 recipients of living related renal transplantation. Statistical analysis of serum creatine in MS and non-MS groups was conducted by SPSS 16.0 software at Month 3/6，Year 1/3/5 post-transplantation. And t-test was utilized for comparing two groups. Logistic regression was applied for risk factor analysis of MS and <italic>P</italic><0.05 was deemed as significant.ResultsNo significant inter-group difference existed in serum creatine at Month 3 post-transplantation. The mean value and standard deviation were （110.5±27.4） and （109.1±34.0） respectively （<italic>P</italic>>0.05）. At Month 6 post-transplantation，the mean value and standard deviation were （119.2±32.7） and （107.4±24.9） respectively （<italic>P</italic>>0.05）. Significant inter-group difference existed in serum creatine at Year 1 post-transplantation. The mean value and standard deviation were （133.6±39.6） and （106.2±19.2） respectively （<italic>P</italic><0.05）. At Year 3 post-transplantation，the mean value and standard deviation were （230.8±221.6） and （110.6±23.8） respectively （<italic>P</italic><0.01）. At Year 5 post-transplantation，the mean value and standard deviation were （266.2±103.1） and （113.6±26.4） respectively （<italic>P</italic><0.01）. Logistic regression revealed that the risk factors of MS were hyperuricemia，high triglyceride and low high density lipoprotein cholesterol.ConclusionMS is an important health problem in the recipients of kidney transplantation. It is imperative to develop targeted health education and intensify health management.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.01.006Living related renal transplantationMetabolic syndromeRenal allograft function |
| spellingShingle | Gu Dong-feng Ding Ya-nan Shen Bei-li Zhao He Liu Rui-yong Qu Qing-shan Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation Linchuang shenzangbing zazhi Living related renal transplantation Metabolic syndrome Renal allograft function |
| title | Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation |
| title_full | Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation |
| title_fullStr | Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation |
| title_full_unstemmed | Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation |
| title_short | Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation |
| title_sort | effect of onset of metabolic syndrome on allograft function in living donor s kidney transplantation |
| topic | Living related renal transplantation Metabolic syndrome Renal allograft function |
| url | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.01.006 |
| work_keys_str_mv | AT gudongfeng effectofonsetofmetabolicsyndromeonallograftfunctioninlivingdonorskidneytransplantation AT dingyanan effectofonsetofmetabolicsyndromeonallograftfunctioninlivingdonorskidneytransplantation AT shenbeili effectofonsetofmetabolicsyndromeonallograftfunctioninlivingdonorskidneytransplantation AT zhaohe effectofonsetofmetabolicsyndromeonallograftfunctioninlivingdonorskidneytransplantation AT liuruiyong effectofonsetofmetabolicsyndromeonallograftfunctioninlivingdonorskidneytransplantation AT quqingshan effectofonsetofmetabolicsyndromeonallograftfunctioninlivingdonorskidneytransplantation |