M6A RNA modification: focusing on non-small cell lung cancer progression, therapeutic strategies and challenges

M6A RNA modification: focusing on non-small cell lung cancer progression, therapeutic strategies and challenges

N6-methyladenosine (m6A) modification is a pivotal mechanism in RNA epigenetics, with profound implications for lung cancer (LC) biology. This review synthesizes current knowledge on m6A’s multifaceted regulatory networks in non-small cell lung cancer (NSCLC), elucidating its roles in tumor prolifer...

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Bibliographic Details
Main Authors: Yuyang Yan, Jiarui Yin, Quan Ding, Yan Lu, Shuhua Gou, Xi Xu, Yulin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
M6A
non-small cell lung cancer
therapeutic strategies
metabolic reprogramming
RNA epigenetic regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1622359/full
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